1995
DOI: 10.3109/17453679508994645
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Proteoglycan degradation in hemarthrosis: Intraarticular, autologous blood injection in rat knees

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Cited by 33 publications
(21 citation statements)
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“…These results are more or less in accordance with those found by Niibayashi et al (1995). They found after intraarticular injection of autologous blood into the knee joints of rats, a higher number of mononuclear cells after 8 h, 1 and 2 days.…”
Section: Discussionsupporting
confidence: 94%
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“…These results are more or less in accordance with those found by Niibayashi et al (1995). They found after intraarticular injection of autologous blood into the knee joints of rats, a higher number of mononuclear cells after 8 h, 1 and 2 days.…”
Section: Discussionsupporting
confidence: 94%
“…There is convincing evidence that the creation of an intra-articular haematoma can lead to damage of the cartilaginous surface (Niibayashi et al, 1995;Roosendaal et al, 1999;Hooiveld et al, 2003Hooiveld et al, , 2004. This has been shown by Hooiveld et al (2003Hooiveld et al ( , 2004 by creating intra-articular haematomas in the knee joints of Beagle dogs.…”
Section: Discussionmentioning
confidence: 86%
“…We employed a battery of tests to characterize pain-related behaviour in a rat model of autologous intraarticular injections as originally described by Niibayashi and coworkers [7]. …”
Section: Discussionmentioning
confidence: 99%
“…In all of these models, however, hardly any spontaneous bleedings into joints are seen [22] and, therefore, they need to be induced, for example, by blunt trauma [23]. For the examination of localized phenomena induced by bleedings, injections of blood in dogs and rats have previously been utilised [7,24]. For our purpose, we chose the latter since, here, bleedings can be simulated in a standardized fashion and variability between animals can thus be kept small (time course, regular testing, blood volume).…”
Section: Discussionmentioning
confidence: 99%
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