2024
DOI: 10.1038/s41598-024-57876-4
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Proteomic analysis of fipronil-induced molecular defects in spermatozoa

Jeong-Won Bae,
Woo-Sung Kwon

Abstract: The phenylpyrazole insecticide fipronil has wide-ranging applications from agriculture to public health to control undesirable organisms. However, several studies have reported the residual environmental hazards of fipronil and demonstrated its harmful effects even in mammalian reproduction. Therefore, this study was conducted to demonstrate the mode of action of fipronil on mouse spermatozoa. We treated fipronil to spermatozoa and performed comprehensive function evaluations. Moreover, proteomic analyses were… Show more

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