Proteomics-based identification of different training adaptations of aged skeletal muscle following long-term high-intensity interval and moderate-intensity continuous training in aged rats

Li, Fanghui; Sun, Lei; Wu, Da-Shuai; Gao, Hao-En; Zhu, Mingyan

doi:10.18632/aging.102044

Cited by 22 publications

(18 citation statements)

References 55 publications

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“…Within 2 wk of training, the rates of exercise avoidance were minimal and electrical shock was no longer required. Exercise training sessions were held at the same time each morning ( 10 , 17 ).…”

Section: Methodsmentioning

confidence: 99%

Lifelong Exercise in Age Rats Improves Skeletal Muscle Function and MicroRNA Profile

Gao

Xie

et al. 2021

Medicine &Amp; Science in Sports &Amp; Exercise

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Section: Methodsmentioning

confidence: 99%

Lifelong Exercise in Age Rats Improves Skeletal Muscle Function and MicroRNA Profile

Gao

Xie

et al. 2021

Medicine &Amp; Science in Sports &Amp; Exercise

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“…showing a marked increase in CS activity in skeletal muscles of the elderly with HIIT interventions [52]. This coincided with improved endurance walking capacity and increased utilization of glucose and lipids, suggesting that the HIIT-induced increase in CS activity and subsequent increase in mitochondrial ATP biosynthesis may exert protective effects against the loss of age-associated endurance performance in older adults.…”

Section: Blood Pressure and Ef%mentioning

confidence: 84%

The Impact of Interval Training on Cardiorespiratory Fitness, Body Composition, Physical Fitness, and Metabolic Parameters in Older Adults: a Systematic Review and Meta-Analysis

Wu¹,

Zhu-ying²,

Gao³

et al. 2020

Preprint

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Background: This review and meta-analysis aimed to evaluate the effects of high-intensity interval training (HIIT) on cardiorespiratory fitness, body composition, physical fitness, and health-related outcomes in older adults. Methods: Four electronic databases (PubMed, Scopus, Medline, and Web of Science) were searched (until Oct 2019) for randomized trials comparing the effect of HIIT on physical fitness, metabolic parameters, and cardiorespiratory fitness in older adults. The Cochrane risk of bias assessment tool was used to evaluate the methodological quality of the included studies; Stata 14.0 software was used for statistical analysis.Results: HIIT significantly improved the maximum rate of oxygen consumption (VO 2max ) compared with a moderate-intensity continuous training (MICT) protocol (HIIT vs. MICT: weighted mean difference = 2.04, 95% confidence interval: 1.01-3.07, p < 0.001). Additional subgroup analyses determined that training periods > 12 wks, training frequencies of 2 sessions/wk, session lengths of 40 min, 6 sets and repetitions, training times per repetition of > 60 s, and rest times of < 90 s are more effective for VO 2max . Conclusions:This systematic review and meta-analysis showed that HIIT induces favorable adaptions in cardiorespiratory fitness, physical fitness, muscle power, cardiac contractile function, and citrate synthase activities in older individuals which may help to maintain aerobic fitness and slow down the process of sarcopenia.

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“…HIIT program can also be used to prevent sarcopenia, a more common syndrome in middle-aged and elderly patients, which is often combined with muscle mass loss, oxidative stress, chronic low-grade inflammatory status, and adipocytokine dysfunction (105,106). Both animal and human experiments (106)(107)(108) showed that HIIT could modulate changes in inflammatory parameters, adipose tissues, and serum, as well as insulin-like growth factor 1 (IGF-1) levels in the skeletal muscle tissue. One recent research (109) also proved that HIIT was an effective training strategy to improve sarcopenia and skeletal muscle vascularization compared with traditional resistance training.…”

Section: Discussionmentioning

confidence: 99%

Bibliometric Review to Explore Emerging High-Intensity Interval Training in Health Promotion: A New Century Picture

You

Liu

et al. 2021

Front. Public Health

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Background: High-intensity interval training (HIIT) is an emerging exercise strategy and is considered to be a recipe for health promotion. This study aimed to systematically identify collaboration networks, track research trends, highlight current hotspots, and predict future frontiers in HIIT and its applications in health promotion since the start of the new century.Methods: Relevant original publications were obtained from the Science Citation Index Expanded of the Web of Science Core Collection (WoSCC) database between 2001 and 2020. CiteSpace and VOSviewer software were used to perform bibliometric visualization and comparative analysis of involved indexes that included countries, institutions, journals, authors, references, and keywords.Results: A total of 572 papers were included, and the trend of annual publications showed a remarkable growth. The United States and the University of Exeter were the most productive country and institutions, respectively, with 107 and 18 publications, respectively. European Journal of Applied Physiology took the lead in the number of published articles, and Medicine and Science in Sports and Exercise ranked first in the cocitation counts. Barker AR and Gibala MJ were considered as the most productive and the most highly-cited authors.Conclusions: “Health risks,” “adolescent,” and “aging” are the three noteworthy topics during the evolution of HIIT-health promotion (HIIT-HP) research. The current research hotspots of HIIT and its practices in the health promotion domain lies in “metabolic diseases,” “cardiovascular diseases,” “neurological diseases,” and “musculoskeletal diseases.” The authors summarize that “prevention and rehabilitation,” “micro and molecular level,” and “cognition and mental health” are becoming frontiers and focus on the health topics related to HIIT in the upcoming years, which are worthy of further exploration.

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Proteomics-based identification of different training adaptations of aged skeletal muscle following long-term high-intensity interval and moderate-intensity continuous training in aged rats

Cited by 22 publications

References 55 publications

Lifelong Exercise in Age Rats Improves Skeletal Muscle Function and MicroRNA Profile

Lifelong Exercise in Age Rats Improves Skeletal Muscle Function and MicroRNA Profile

The Impact of Interval Training on Cardiorespiratory Fitness, Body Composition, Physical Fitness, and Metabolic Parameters in Older Adults: a Systematic Review and Meta-Analysis

Bibliometric Review to Explore Emerging High-Intensity Interval Training in Health Promotion: A New Century Picture

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