2004
DOI: 10.1016/s0035-9203(03)00065-8
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Protocol and monitoring to improve snake bite outcomes in rural Ghana

Abstract: A study was conducted in Mathias Hospital, Yeji, an area of Ghana, where snake bite cases are an important cause of morbidity and mortality, with a case fatality rate of 11% (8/72). Case management difficulties included uncertainty about the assessment of the severity of envenoming, the dosage of antivenom, and the response to treatment. An intervention with several components was introduced: development of a treatment protocol, staff training, monitoring of compliance and patient education. During a 33-month … Show more

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Cited by 44 publications
(53 citation statements)
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“…The population of Savelugu-Nanton District was ∼130,000, constituting ∼6% of the population of the Northern Region of Ghana in 2008 [17], so we conservatively estimate about 1,700-12,500 envenomations with about 50-350 fatalities annually (mortality rate of ∼3%) in this part of the country. This figure makes up about 20-95% of a Ghana national estimate of about 250-375 [40], and is within the range of current available estimates for the sub-region [1, 9] and other estimates from northern [23] and central [22, 42] Ghana, but 5-10 times higher than southwest Ghana [24].…”
Section: Discussionsupporting
confidence: 72%
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“…The population of Savelugu-Nanton District was ∼130,000, constituting ∼6% of the population of the Northern Region of Ghana in 2008 [17], so we conservatively estimate about 1,700-12,500 envenomations with about 50-350 fatalities annually (mortality rate of ∼3%) in this part of the country. This figure makes up about 20-95% of a Ghana national estimate of about 250-375 [40], and is within the range of current available estimates for the sub-region [1, 9] and other estimates from northern [23] and central [22, 42] Ghana, but 5-10 times higher than southwest Ghana [24].…”
Section: Discussionsupporting
confidence: 72%
“…With a large sample size of 1,024 respondents covering both dry and wet seasons, and a retrospective 10-year bivariate data sample of snakebite incidences and rainfall patterns, our study represents an important contribution to epidemiological snakebite studies for this region. Previous epidemiological studies have largely been limited to short-term data series with lower sample sizes of predominantly retrospective hospital records for Ghana [22, 23, 24] and sub-Saharan Africa [25, 26, 27, 28, 29], where complementary or nationwide long-term published studies remain scarce [1, 16, 30, 31]. Estimates of regional or national snakebite burdens based exclusively on hospital records inevitably neglect many snakebite cases treated at home or by TMPs [1, 4, 16, 30].…”
Section: Discussionmentioning
confidence: 99%
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“…Outcomes in snakebite have repeatedly been shown to be positively influenced by increased knowledge of snakebite amongst local practitioners. 34,35 …”
Section: Resultsmentioning
confidence: 99%
“…Their importance must not be under-estimated even in the presence of adequate amounts of specific anti-venoms [1]. In a study in Ghana, the institution of an intervention package for snake bite management, comprising: treatment protocol, staff training, monitoring of compliance and patient education, saw a 50% increase in snake bite admissions and a 90% decrease in mortality from snake bites, over a 15 month period [32]. A similar intervention could be expected to have a similar effect in our setting.…”
Section: Discussionmentioning
confidence: 99%