“…Three systematic reviews and meta-analyses [14e16] on the effects of protocol-directed sedation have recently been published. The two systematic reviews and meta-analyses [14,15] in 2017 and 2018 acquired limited evidence from randomised controlled trial (RCT) studies (only two and four RCTs, respectively) that assessed the effects of protocol-directed sedation on patient outcomes. One systematic review and meta-analysis published in 2015 [16] including RCTs and preintervention and postintervention studies found no difference in the MV period and patient's length of stay in the ICU between nurse-led sedation protocols and usual care led by physicians.…”
Please cite this article as: Qi Z et al., Effects of nurse-led sedation protocols on mechanically ventilated intensive care adults: A systematic review and meta-analysis, Australian Critical Care,
“…Three systematic reviews and meta-analyses [14e16] on the effects of protocol-directed sedation have recently been published. The two systematic reviews and meta-analyses [14,15] in 2017 and 2018 acquired limited evidence from randomised controlled trial (RCT) studies (only two and four RCTs, respectively) that assessed the effects of protocol-directed sedation on patient outcomes. One systematic review and meta-analysis published in 2015 [16] including RCTs and preintervention and postintervention studies found no difference in the MV period and patient's length of stay in the ICU between nurse-led sedation protocols and usual care led by physicians.…”
Please cite this article as: Qi Z et al., Effects of nurse-led sedation protocols on mechanically ventilated intensive care adults: A systematic review and meta-analysis, Australian Critical Care,
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