Protocol for a systematic review and meta-analysis of interventions for pathologic perforator veins in chronic venous disease

Silva, Melissa Andreia de Moraes; Flumignan, Ronald Luiz Gomes; Miranda, Fausto; Cardoso, Rodolfo Souza; Jesus-Silva, Seleno Glauber de; Guedes, Henrique; Nakano, Luís Carlos Uta

doi:10.1136/bmjopen-2018-024088

Cited by 1 publication

(3 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Complications of US guided sclerotherapy include, but are not limited to, allergic reaction, superficial thrombophlebitis, septic thrombophlebitis, DVT, and rarely localized skin necrosis. 5,15,21 We demonstrated septic thrombophlebitis in one patient. Since CA is a non-absorbable foreign body, sepsis can be potentially difficult to eradicate.…”

Section: Discussionmentioning

confidence: 76%

“… 1 IPV are known to play a significant role in not only the advancement but also the recurrence of lower limb venous insufficiency. 2 – 5 Despite this, there continues to be no clear consensus regarding the best treatment or indication for treatment for IPV. 2 , 4 , 6 Treatment of perforators in CEAP class 2 and class 3 patients is debatable, however, clinical practice guidelines of the Society for Vascular Surgery and the American Venous Forum recommend treatment of perforating veins with reflux >500 ms and a vein diameter >3.5 mm located near healed or active venous ulcers.…”

Section: Introductionmentioning

confidence: 99%

“…7 In addition, multiple modalities for the treatment of IPV are found in the SVS and AVF clinical practice guidelines including surgery such as subfascial endoscopic perforator surgery (SEPS), thermal ablation (laser and radiofrequency) and ultrasound (US) guided foam sclerotherapy. 7 At our centers, patients with advanced chronic venous insufficiency (CEAP class [5][6], IPV in the vicinity or underneath an ulcer are treated simultaneous with any superficial long axial reflux. We feel that simultaneous treatment of IPV plus superficial long axial reflux in CEAP class 2-4 patients with a supportive Brodie-Trendelenburg test results in improved symptom control and less need for completion treatments or staged perforator treatments.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Ultrasound-guided cyanoacrylate injection for the treatment of incompetent perforator veins

et al. 2021

View full text Add to dashboard Cite

Objective The use of cyanoacrylate products (CA) in incompetent perforator vein (IPV) treatment has not been thoroughly examined. The primary objective of this study is to describe the technique of ultra sound guided direct injection of IPV with CA, and secondarily to determine early closure rates and safety of this technique. Methods A retrospective analysis of patients undergoing IPV injection at two centres between 2015-2018 was conducted. Demographics, CEAP classification and IPV location were collected. Outcomes were assessed at two follow-up appointments. Results A total of 83 perforator vein injections were completed. CEAP classifications include C2 – C6 classes. Location of perforators were posteromedial (6%), femoral canal (9%), paratibial (14%), and posterior-tibial (71%). IPV closure rates were 96.3% at initial follow-up (16 ± 2 days). Closure rates decreased to 86.5% at second follow-up (72 ± 9 days). There were no deep vein thromboses during follow-up. One patient developed septic thrombophlebitis that was successfully managed with antibiotics. Conclusion Ultrasound-guided CA glue injection is a simple and low risk procedure that effectively closes incompetent perforator veins.

show abstract

Section: Discussionmentioning

confidence: 76%