Protocol for The International Cohort on Lifestyle Determinants of Health Study: A Longitudinal Investigation of Complementary and Integrative Health Utilization in Postsecondary Education Students

Bradley, Ryan; Pickworth, Courtney K.; Wexler, Ryan S; Sadowski, Adam; Buttolph, Lita; Sarrar, Hadil; Moehle, Jillian; Torrens, M.; Harnett, Joanna; McIntyre, Erica; Schloss, Janet; Steel, Amie; Adams, Jon

doi:10.1089/acm.2020.0419

Cited by 3 publications

(5 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This study is a secondary analysis of the International Cohort on Lifestyle Determinants of Health (INCLD Health) cohort data, the methods of which have been previously described [ 32 ]. While the INCLD Health longitudinal cohort study collected data on various aspects of health and wellness, diet, and the gut microbiome over several time points at 6-month intervals, this secondary analysis only includes data from the baseline visit analyzed in a cross-sectional manner.…”

Section: Methodsmentioning

confidence: 99%

Relationships between Habitual Polyphenol Consumption and Gut Microbiota in the INCLD Health Cohort

Vita,

Roberts,

Gundersen

et al. 2024

Nutrients

Self Cite

View full text Add to dashboard Cite

While polyphenol consumption is often associated with an increased abundance of beneficial microbes and decreased opportunistic pathogens, these relationships are not completely described for polyphenols consumed via habitual diet, including culinary herb and spice consumption. This analysis of the International Cohort on Lifestyle Determinants of Health (INCLD Health) cohort uses a dietary questionnaire and 16s microbiome data to examine relationships between habitual polyphenol consumption and gut microbiota in healthy adults (n = 96). In this exploratory analysis, microbial taxa, but not diversity measures, differed by levels of dietary polyphenol consumption. Taxa identified as exploratory biomarkers of daily polyphenol consumption (mg/day) included Lactobacillus, Bacteroides, Enterococcus, Eubacterium ventriosum group, Ruminococcus torques group, and Sutterella. Taxa identified as exploratory biomarkers of the frequency of polyphenol-weighted herb and spice use included Lachnospiraceae UCG-001, Lachnospiraceae UCG-004, Methanobrevibacter, Lachnoclostridium, and Lachnotalea. Several of the differentiating taxa carry out activities important for human health, although out of these taxa, those with previously described pro-inflammatory qualities in certain contexts displayed inverse relationships with polyphenol consumption. Our results suggest that higher quantities of habitual polyphenol consumption may support an intestinal environment where opportunistic and pro-inflammatory bacteria are represented in a lower relative abundance compared to those with less potentially virulent qualities.

show abstract

Section: Methodsmentioning

confidence: 99%

Relationships between Habitual Polyphenol Consumption and Gut Microbiota in the INCLD Health Cohort

Vita,

Roberts,

Gundersen

et al. 2024

Nutrients

Self Cite

View full text Add to dashboard Cite

show abstract

“…This study is a secondary analysis of data collected during the INCLD Health longitudinal cohort study, the methods of which have been previously published [27]. Briefly, data from participants was collected over the course of three time points-baseline, 6 months, and 1 year-and included various evaluations of health, wellness, lifestyle, diet, and the microbiome.…”

Section: Methodsmentioning

confidence: 99%

“…Participants in the original study were students enrolled in a complementary and integrative medicine education program and were previously recruited through methods outlined in the INCLD Health protocol [27]. While data was collected from 197 participants during the INCLD Health study, data from only 96 of those participants were used in the statistical analyses of this ancillary study for reasons outlined under the "Statistical models" sub-section.…”

Section: Participantsmentioning

confidence: 99%

Associations between Frequency of Culinary Herb Use and Gut Microbiota

et al. 2022

Self Cite

View full text Add to dashboard Cite

While evidence suggests that culinary herbs have the potential to modulate gut microbiota, much of the current research investigating the interactions between diet and the human gut microbiome either largely excludes culinary herbs or does not assess use in standard culinary settings. As such, the primary objective of this study was to evaluate how the frequency of culinary herb use is related to microbiome diversity and the abundance of certain taxa, measured at the phylum level. In this secondary data analysis of the INCLD Health cohort, we examined survey responses assessing frequency of culinary herb use and microbiome analysis of collected stool samples. We did not observe any associations between frequency of culinary herb use and Shannon Index, a measure of alpha diversity. Regarding the abundance of certain taxa, the frequency of use of polyphenol-rich herbs and herbs with certain quantities of antibacterial compounds was positively associated with Firmicutes abundance, and negatively associated with Proteobacteria abundance. Additionally, the total number of herbs used with high frequency, defined as over three times per week, was also positively associated with Firmicutes abundance, independent of adjustments, and negatively associated with Proteobacteria abundance, after adjusting for dietary factors. Frequency of culinary herb use was not associated with Bacteroidota or Actinobacteria abundance.

show abstract

“…This study follows the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) checklist for cross-sectional studies [42]. The protocol, including data collection instruments and procedures, for the INCLD Health Cohort has been described previously [40]. Briefly, INCLD Health is an ongoing, prospective cohort of English speaking, post-secondary education students, at least 18 years of age, enrolled in accredited CIH education programs from one to six years in length and not in their final year of education (i.e., students in their final year of a four-year program at time of recruitment).…”

Section: Design Setting and Participantsmentioning

confidence: 99%

“…The present study is an ancillary secondary analysis of data collected within the International Cohort on Lifestyle Determinants of Health (INCLD Health) study [40]. This research aimed to (1) evaluate the associations of perceived stress, sleep disturbance, and meditative practices with diurnal cortisol, and (2) identify associations of meditative and mind-body practices with perceived stress and sleep disturbance in students receiving CIH education.…”

Section: Introductionmentioning

confidence: 99%

Meditative practices, stress and sleep among students studying complementary and integrative health: a cross-sectional analysis

Sadowski

Wexler

Hanes

et al. 2022

BMC Complement Med Ther

Self Cite

View full text Add to dashboard Cite

Background The International Cohort on Lifestyle Determinants of Health (INCLD Health) is an ongoing, prospective cohort study assessing the health behaviours and lifestyles of higher education students, including their use of specialty diets and complementary and integrative health (CIH) practices. Purpose: This cross-sectional analysis of the INCLD Health cohort aims to (1) evaluate the associations between perceived stress, sleep disturbance, and meditative practices with diurnal salivary free cortisol and (2) evaluate the associations of meditative practices as well as mind-body practices with perceived stress and sleep disturbance. Methods Serial multivariable linear regression models, adjusting for sociodemographic and lifestyle behaviours, were used to assess associations of (1) perceived stress, sleep disturbance, and meditative practices with salivary cortisol, and (2) meditative practices as well as mind-body practices with perceived stress and sleep disturbance. Meditative and mind-body practices were evaluated using a stress-management and self-care survey; perceived stress and sleep disturbance were evaluated using the 10-item Perceived Stress Scale (PSS), and the patient reported outcome measures information system-29 (PROMIS-29) sleep sub-score respectively. Salivary cortisol was collected at 4 time points over a 24-hour period and area under the curve (AUC) calculations conducted. Results 82.5% (n = 80) of participants utilized at least monthly meditative practices. Greater disturbed sleep, but not perceived-stress, meditative, nor mind-body practices was independently associated with increased AUC cortisol (b = 0.02, 95% CI: 0.002–0.05, p = 0.03) after adjusting for age, sex, race, ethnicity, and BMI. Neither meditative nor mind-body practices were associated with perceived stress or disturbed sleep. Conclusions Among INCLD Health participants, greater sleep disturbance, but not perceived stress or meditative practices were associated with daytime cortisol.

show abstract

Protocol for The International Cohort on Lifestyle Determinants of Health Study: A Longitudinal Investigation of Complementary and Integrative Health Utilization in Postsecondary Education Students

Cited by 3 publications

References 27 publications

Relationships between Habitual Polyphenol Consumption and Gut Microbiota in the INCLD Health Cohort

Relationships between Habitual Polyphenol Consumption and Gut Microbiota in the INCLD Health Cohort

Associations between Frequency of Culinary Herb Use and Gut Microbiota

Meditative practices, stress and sleep among students studying complementary and integrative health: a cross-sectional analysis

Contact Info

Product

Resources

About