Proton magnetic resonance and human thyroid neoplasia I: Discrimination between benign and malignant neoplasms

From magnetic resonance spectroscopy to classification of tumors. A review of pattern recognition methods

“…Only in some studies, have single resonances or ratios of resonance ranges been reported to have a discriminatory power. [2][3][4][5][6][7]14 In parallel, reports about patterns of spectral changes associated with given tumor types, [8][9][10][11][12][13][14][15] celltypes [16][17][18] and disease states 19 have been published. To permit the analysis of tumor specific MRS patterns and their use for tumor classification, several methods, denoted pattern recognition (PR) methods, are available.…”

Enhanced resolution of proton NMR spectra of malignant lymph nodes using magic‐angle spinning

“…This averaging does not occur in solids or is incomplete in systems with restricted or anisotropic motion. The first-order dipolar interaction is proportional to 3cos'fj -1, where 8 is the angle between the static magnetic field B,, and the internuclear vector. If the sample is mechanically spun at an angle 0' = 54"44' relative to B, (ix., the "magic-angle" where :3coszfj' -1 = 0 ) and at a rate that is fast compared with the inverse of the dipolar coupling, the contribution of the dipolar interaction to the signal linewidth will be greatly reduced.…”

Thyroid Follicular Neoplasms Diagnosed by High-Resolution Ultrasonography with Fine Needle Aspiration Cytology

“…8 Although there is new methodology for evaluating follicular lesions before surgery, the results are not satisfactory, with a specificity of only 52%. 9 Unlike other well-differentiated thyroid carcinomas, there is no characteristic finding in FNAC of follicular thyroid cancer. Until now, we did not have enough information about the final histopathologic results on follicular neoplasms.…”