Chiral symmetry is one of the most fundamental symmetries in QCD. It is closely connected to hadron properties in the nuclear medium via the reduction of the quark condensate , manifesting the partial restoration of chiral symmetry. To better understand this important issue, a number of Jefferson Lab experiments over the past decade have focused on understanding properties of mesons and nucleons in the nuclear medium, often benefiting from the high polarization and luminosity of the CEBAF accelerator. In particular, a novel, accurate, polarization transfer measurement technique revealed for the first time a strong indication that the bound proton electromagnetic form factors in 4 He may be modified compared to those in the vacuum. Second, the photoproduction of vector mesons on various nuclei has been measured via their decay to e + e − to study possible in-medium effects on the properties of the ρ meson. In this experiment, no significant mass shift and some broadening consistent with expected collisional broadening for the ρ meson has been observed, providing tight constraints on model calculations. Finally, processes involving in-medium parton propagation have been studied. The medium modifications of the quark fragmentation functions have been extracted with much higher statistical accuracy than previously possible. the density and temperature dependence of hadron properties in the nuclear medium. However, current simulations have just started to study the 2-body, nucleon-nucleon [2] and nucleonhyperon interactions [3], which is still very far from what is needed for the description of a finite nucleus. At present, although one is forced to rely on some models, it is a very important step to understand the main features of nuclear phenomena and the structure of finite nuclei based on the quark and gluon degrees of freedom [4].We know that explicit quark degrees of freedom are certainly necessary to understand deepinelastic scattering (DIS) at momentum transfers of several GeV. In particular, the nuclear EMC effect [5] has suggested that it is vital to include some dynamics beyond the conventional nucleon-meson treatment of nuclear physics to explain the nuclear structure function data [6,7]. This leads to the extraction of nuclear parton, or bound-nucleon parton distributions [8,9]. Inmedium structure functions were studied at Jefferson Lab in an EMC-type experiment in heavy nuclei, emphasizing the large-x region [10,11], and recently also in few-body nuclei [12,13]. Another series of Jefferson Lab experiments focus on the longitudinal-transverse separation of in-medium structure functions [14,15].Furthermore, the search for evidence of some modification of nucleon properties in medium has recently been extended to the nucleon electromagnetic form factors in polarized ( e, e ′ p) scattering experiments on 16 O [16, 17] and 4 He [18,19,20,21,22] nuclei at MAMI and Jefferson Lab. These experiments observed the double ratio of proton-recoil polarization transfer coefficients in the scattering off nuclei wit...