Purpose: This study investigated knowledge of atopic dermatitis and food allergies, as well as health information literacy, among North Korean refugee mothers with preschool-age children and explored how these variables were related to participants' characteristics.Methods: A descriptive study design was used. Data from 130 North Korean refugee mothers were collected between January and March 2023.Results: The mean scores were 14.48 of 30 for atopic dermatitis knowledge; 2.77 of 10 for food allergy knowledge, and 56.95 of 80 for health information literacy. Significant differences were observed in knowledge of atopic dermatitis based on breastfeeding duration (F=4.12, <i>p</i>=.009), and in knowledge of food allergies based on mixed feeding (F=3.11, <i>p</i>=.049). Health information literacy showed significant relationships with education level (F=3.76, <i>p</i>=.026), occupation (F=3.99, <i>p</i>=.021), checking nutritional information (t=2.91, <i>p</i>=.004), mixed feeding (F=4.50, <i>p</i>=.014), and atopic dermatitis diagnosis (t=6.86, <i>p</i>=.001). Significant positive correlations were observed between atopic dermatitis knowledge, food allergy knowledge, and health information literacy.Conclusion: Personalized educational programs should be implemented to improve awareness of allergies and health information literacy among North Korean refugee mothers, which would help them find, evaluate, and understand health-related information. These programs should focus on providing nutrition and dietary education to promote healthy growth in children and prevent diseases.