The American College of Clinical Pharmacy (ACCP) endorses comprehensive medication management (CMM) as an essential element of team‐based care and advocates CMM inclusion in value‐based health care reform. Remote delivery of CMM through telehealth platforms is expanding and has the potential to become one of the most common clinical pharmacy services. Building on a previous ACCP publication, “Providing Comprehensive Medication Management in Telehealth,” the 2019 ACCP Clinical Practice Affairs A Committee provides insights and guidance on developing, implementing, evaluating, and improving CMM telehealth practices in this white paper.