Proximate Analysis of Moringa oleifera Leaves and the Antimicrobial Activities of Successive Leaf Ethanolic and Aqueous Extracts Compared with Green Chemically Synthesized Ag-NPs and Crude Aqueous Extract against Some Pathogens

Abstract

Research on the use of different parts of the Moringa oleifera plant as a nutritional and pharmaceutical resource for human and animals has increased in recent years. This study aimed to investigate the chemical composition and the TPCs and TFCs of Moringa leaves, the antimicrobial activities of Moringa successive ethanolic, aqueous, crude aqueous extracts, and green-chemically synthesized characterized Ag-NPs. The results indicated that the ethanolic extract recorded the highest activity against E. coli. On the other side, the aqueous extract showed higher activity, and its effects ranged from 0.03 to 0.33 mg/mL against different strains. The MIC values of Moringa Ag-NPs against different pathogenic bacteria ranged from 0.05 mg/mL to 0.13 mg/mL, and the activity of the crude aqueous extract ranged from 0.15 to 0.83 mg/mL. For the antifungal activity, the ethanolic extract recorded the highest activity at 0.04 mg/mL, and the lowest activity was recorded at 0.42 mg/mL. However, the aqueous extract showed effects ranging from 0.42 to 1.17 mg/mL. Moringa Ag-NPs showed higher activity against the different fungal strains than the crude aqueous extract, and they ranged from 0.25 to 0.83 mg/mL. The MIC values of the Moringa crude aqueous extract ranged from 0.74 to 3.33 mg/mL. Moringa Ag-NPs and their crude aqueous extract may be utilized to boost antimicrobial attributes.

Comparative Extraction and Bioactive Potential of the Leaf Extracts of Azadirachta indica for Combatting Postoperative Head and Neck Infections: An In Vitro Study

“…In our investigation, ethanol extracts of A. indica were shown to be more sensitive than standard erythromycin as an antibiotic. A. indica stem bark extracts also showed considerable antioxidant activity, establishing the extracts' function as antioxidants [ 13 - 15 ]. Similarly, ethanolic extracts of neem leaf showed increased antioxidant activity compared with the aqueous extracts.…”

Natural Medicine: In-Depth Exploration of Moringa oleifera’s Bioactive Compounds and Antimicrobial Effects

“…Moringa oleifera leaves (MOL) exhibit significant antimicrobial effects against a wide range of bacterial species, including both Gram-positive (e.g., Staphylococcus aureus, Enterococcus faecalis) and Gram-negative (e.g., Escherichia coli, Pseudomonas aeruginosa) strains [19,20]. This antimicrobial action is attributed to the inhibition zones generated by the disc diffusion method, indicative of the effectiveness of MOL against various organisms.…”

Green synthesized silver nanoparticles for the treatment of diabetes and the related complications of hyperlipidemia and oxidative stress in diabetic rats

“…19 Using the biological nanoparticle sources is important for nanoscale material development, and technical tools that can be used to develop ecofriendly and reliable methodologies to synthesize such materials. [20][21][22] Accordingly, we aimed to synthesize green silver nanoparticles using cinnamon extracts (C-Ag-NPs) and study the physical and chemical characteristics of the composite nanoparticles, and to assess the biological ecofriendliness of the nanoparticles when controlling the hyperglycemic conditions and related complications disorders in streptozotocin (STZ)-induced diabetic rats.…”