Proximate and phytochemical composition of Phyllantus amarus

Achikanu, None CE; Ujah, Innocent Izuchukwu; Ezenwali, None MO

doi:10.30574/wjarr.2022.15.1.0517

Cited by 3 publications

(7 citation statements)

References 17 publications

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“…As well as its contained food bers which have been shown to aid the absorption of dietary minerals as well as reduce the absorption of cholesterol and help to maintain blood sugar. Diets rich in bres helps to prevent constipation, support the health of the digestive tract as well as avert colon cancer [30]. Dietary bres is not an essential nutrient because it does not have an energy function.…”

Section: Nutritional and Mineral Compositions Of A Garckeana Leaves T...mentioning

confidence: 99%

“…The ash content gives a measure of total amount of inorganic compounds like minerals present in a food [29]. Mineral elements are the essential constituents of ash [30]. Fat is one of the major component causing differences in the gross energy of various food substance, it yields over 9 Kcal/g compared to carbohydrates and proteins that yield about 4 kcal/g [12].…”

Section: Nutritional and Mineral Compositions Of A Garckeana Leaves T...mentioning

confidence: 99%

“…The moisture content is a major determinant in the healing, safeguarding and sustenance of food and drug. A high moisture value will promote the activities of spoilage microorganisms and result in reduced shelf life [30]. The results showed that the leaves sample of A. garckeana have a minimal moisture content and considerable amount of ash content which are very important factors required for checking quality for both utilization and storage purposes.…”

Section: Nutritional and Mineral Compositions Of A Garckeana Leaves T...mentioning

confidence: 99%

“…Thus, the presence of these antinutrients in the evaluated leaves samples of A. garckeana plant may interfere with their bioavailability and decrease their nutritive values. For example, the presence of oxalate in food is known to interfere with the assimilation of nutrients, decrease the nutritive value of the food at high doses and may have adverse effects on human health [30]. Higher content of oxalate can bind to calcium present in food, thereby rendering calcium unavailable for normal physiological, and biochemical role such as the maintenance of strong bone, teeth, cofactor in enzymatic reaction, nerve impulse transmission, and as clotting factor in the blood.…”

Section: The Anti-nutrient Compositions Of a Garckeana Leavesmentioning

confidence: 99%

“…Phytate is of therapeutic use against diabetes mellitus, atherosclerosis, and coronary heart disease and reduces kidney stone formation, HIV-1, and heavy metal toxicity. However, information on the dosage for humans for eliciting bene cial effects is limited [39,30]. Iron bound with phytate is presumably unavailable for absorption and uptake by the human intestine [40].…”

Section: The Anti-nutrient Compositions Of a Garckeana Leavesmentioning

confidence: 99%

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Assessment of Nutrients, Antinutrients and In Vitro Antioxidants Studies of Whole Leaf, and Leaf Extract of Azanza garckeana

Felix,

Nkwocha,

Oruchukwu

2024

Preprint

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Plants-derived functional foods have been a significant source of nutrients and medicinal compounds. The purpose of this study was to evaluate the nutritional values, antinutrients compositions, and in vitro antioxidants activities of methanolic leaf extract of Azanza garckeana. The analysis were carried out using standard analytical methods. Results of the proximate compositions were carbohydrates (69.18 %), protein (10.51 %), fats (7.33 %), fibres (5.27 %), moisture (4.38 %), and ash (3.57 %). The total energy value was 384.7 kcal/g. The vitamins analysis showed the presence of vitamin A (1.876±0.060 mg/100g), C (0.050±0.012 mg/100g), E (0.606±0.009 mg/100g), D (0.197±0.076 mg/100g), K (0.164±0.012 mg/100g), B1 (0.739±0.019 mg/100g), B2 (0.37±0.005 mg/100g), B3 (0.155±0.033 mg/100g), B6 (0.446±0.022 mg/100g) and vitamin B12 (0.157± 0.0026 mg/100g). The mineral compositions revealed the presence of sodium (815.287 ± 0.004 mg/100g), calcium (731.515 ± 0.003 mg/100g) and copper (1.048 ± 0.008 mg/100g). Antinutrients composition revealed phytate (1.567 ± 0.005 mg/100g), trypsin inhibitor (0.383±0.006 Tiu/mg), oxalate (0.867 ± 0.003 mg/100g), hemaglutinin (0.741 ± 0.004 Hui/mg), and saponins (0.546 ± 0.004 mg/100g). The antioxidants activity of the methanolic crude extract of A. garckeana leaf showed that the total antioxidants capacity (TAC) of the plant extract increased in concentration when compared to the standard antioxidant (ascorbic acid). While the methanolic leaf extract exhibited higher FRAP activity across all the concentrations when compared with the standard antioxidant - butylated hydroxytoluene (BHT). The results of the present study showed that the evaluated leaves of A. garckeana plant is rich in nutritional values, have potent antioxidants and essential nutrients with therapeutics properties.

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Section: Nutritional and Mineral Compositions Of A Garckeana Leaves T...mentioning

confidence: 99%

Section: Nutritional and Mineral Compositions Of A Garckeana Leaves T...mentioning

confidence: 99%

Section: Nutritional and Mineral Compositions Of A Garckeana Leaves T...mentioning

confidence: 99%

Section: The Anti-nutrient Compositions Of a Garckeana Leavesmentioning

confidence: 99%

Section: The Anti-nutrient Compositions Of a Garckeana Leavesmentioning

confidence: 99%

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Assessment of Nutrients, Antinutrients and In Vitro Antioxidants Studies of Whole Leaf, and Leaf Extract of Azanza garckeana

Felix,

Nkwocha,

Oruchukwu

2024

Preprint

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Phytochemical screening and GC-FID identification of bioactive compounds in n-hexane, ethylacetate and methanol fractions of methanolic leaves extract of Azanza garckeana

Nkwocha,

Felix,

Michael

et al. 2024

Food Chemistry Advances

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Ameliorative Effect of Methanol Leaf Extract of Phyllanthus nirurion Anaemic Male Wister Rats

Ifeoluwa,

Abah,

Ale

et al. 2023

Res. J. Med. Plants

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Background and Objective: Anaemia is a major public health problem which affects people of all ages, especially pregnant women and children. It is effectively treated by blood transfusion but a less expensive and easy approach for remedying anaemia is by the administration of oral supplements, for example, the use of plant extract with active secondary metabolites possessing anti-anaemic properties most especially in cases of iron deficiency anaemia. This study was aimed at investigating the ameliorative effect of methanol extract of Phyllanthus niruri on anaemic male Wister albino rats. Materials and Methods: Samples of fresh Phyllanthus niruri whole plant (roots, stems, leaves and seeds) were collected from Wukari, Taraba State, Nigeria. The plant samples were shade dried for 10 days. The dried samples were ground to powder with the aid of a mortar and pestle. The coarse materials were then sieved. Extraction of P. niruri was done by cold maceration with 100% methanol. Twenty male Wister rats were grouped into four groups (n = 5) and acclimatized for 7 days. Anaemia was induced by intraperitoneal injection of phenylhydrazine at 40 mg/kg/b.wt., on days 0 and 1. Packed cell volume (PCV) was determined to ensure induction of anaemia. Group 1 received no treatment, group 2 received ferrous sulphate at 75 mg/kg/b.wt. and groups 3 and 4 received 100 mg/kg/b.wt. and 200 mg/kg/b.wt., of methanolic extract of Phyllanthus niruri, respectively. Results: A significant (p<0.05) decrease in weight in groups 1 and 2 animals was observed. Animals whose PCV decreased by 29% were considered anaemic. The PCV levels on days 1 and 2 showed no significant (p>0.05) difference between groups, while a statistically significant (p<0.05) difference in PCV levels was observed on day 19. There was a significant (p<0.05) increase in PCV, platelet and eosinophil in groups 3 and 4. Other haematological parameters were not significantly different (p>0.05) between groups. Conclusion: The results suggested that the methanolic extract of P. niruri plant is relatively safe and possesses a significant anti-anaemic property. Therefore, it may be a potential lead in the discovery of drugs for the treatment of heamolytic anaemia.

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Proximate and phytochemical composition of Phyllantus amarus

Cited by 3 publications

References 17 publications

Assessment of Nutrients, Antinutrients and In Vitro Antioxidants Studies of Whole Leaf, and Leaf Extract of Azanza garckeana

Assessment of Nutrients, Antinutrients and In Vitro Antioxidants Studies of Whole Leaf, and Leaf Extract of Azanza garckeana

Phytochemical screening and GC-FID identification of bioactive compounds in n-hexane, ethylacetate and methanol fractions of methanolic leaves extract of Azanza garckeana

Ameliorative Effect of Methanol Leaf Extract of Phyllanthus nirurion Anaemic Male Wister Rats

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