Pruritic porokeratotic peno-scrotal plaques: Porokeratosis or porokeratotic epidermal reaction pattern? A report of 10 cases

Joshi, Rajiv; Mehta, Sudhanshu G

doi:10.4103/0378-6323.125474

Cited by 7 publications

(9 citation statements)

References 4 publications

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“…[ 5 ] reported a case of a 28-year-old African American man who presented with pruritic erythematous plaques on the scrotum that showed multiple cornoid lamellae and considered it to be a variant of porokeratosis ptychotropica occurring on the scrotum. This case is very similar to our case and to the series of cases of penoscrotal porokeratosis described earlier[ 1 ] and should be considered as penoscrotal porokeratosis and not a variant of porokeratosis ptychotropica.…”

Section: Discussionsupporting

confidence: 91%

“…Histologically, multiple cornoid lamellae are seen arising from the epidermis as well as from acrosyringia and follicular infundibula. [ 1 ] These multiple cornoid lamellae are seen in biopsies both from the penis and from the scrotum and may be responsible for the granular or pebbly surface seen clinically.…”

Section: Discussionmentioning

confidence: 99%

“…Recently, a series of cases of penoscrotal porokeratotic plaques has been described in young men in their twenties, who had identical clinical presentation of pruritic plaques on the penis and anterior scrotum with multiple cornoid lamellae on histopathology. [ 1 ]…”

Section: Introductionmentioning

confidence: 99%

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Penoscrotal porokeratosis: A distinct entity

Joshi¹,

Jadhav²

2015

Indian Dermatol Online J

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A 26-year-old man presented with five months history of redness associated with itching and burning over the scrotum and shaft of the penis with a persistent rash on those sites. There had been no response to topical steroid and antifungal creams. Clinical examination revealed a large well-circumscribed erythematous plaque with a thready raised border with a tiny groove at its summit that involved almost two-thirds of the ventral part of the shaft of the penis. Ill-defined erythema with a granular surface was seen over the anterior scrotal skin. A 4 mm punch biopsy of the plaque on the penile shaft revealed multiple cornoid lamellae located adjacent to one another. The patient was treated with topical emollients. Follow up after four months revealed almost complete resolution of the plaque on the penile shaft. Penoscrotal porokeratosis appears to be a distinct entity in the family of porokeratotic diseases, described only in young males in their twenties with involvement of the penile shaft and anterior scrotum with severe burning and itching and histologically associated with multiple cornoid lamellae. It may represent an unusual epidermal porokeratotic reaction pattern and may be a self-resolving condition.

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Section: Discussionsupporting

confidence: 91%

Section: Discussionmentioning

confidence: 99%

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Penoscrotal porokeratosis: A distinct entity

Joshi¹,

Jadhav²

2015

Indian Dermatol Online J

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“…Repeated minor frictional trauma due to tight-fitting underclothes or a contact reaction to some agent may be the factors in the pathogenesis of these lesions. Joshi and Mehta 7 described 10 young males who presented with pruritic plaques on the penoscrotal region of several months duration with a clinical appearance not being typical of porokeratosis of Mibelli. They had partly well defined to poorly defined plaques on the ventral surfaces of the penile shaft and the anterior scrotum ( Figures 4 and 5 ).…”

Section: Genitogluteal Porokeratosismentioning

confidence: 99%

“…Presence of cornoid lamellae without typical clinical appearance of annular papules or plaques has been suggested to be an epidermal reaction pattern that may be steroid responsive 6 or long-standing. 7 …”

Section: Introductionmentioning

confidence: 99%

Genitogluteal porokeratosis: a clinical review

Joshi¹,

Minni²

2018

CCID

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Porokeratosis is an uncommon disorder of keratinization that presents with keratotic papules or annular plaques that expand centrifugally with a thread-like elevated border. A distinctive histologic structure, the cornoid lamella, is diagnostic of this disorder and consists of a column of parakeratosis with the absence of the granular layer and dyskeratotic cells in the upper spinous zone. Porokeratosis confined to the genitogluteal region is rare and may be subclassified into three types, namely, classical porokeratosis on the genital region, ptychotropic porokeratosis most often seen in the natal cleft and buttocks and penoscrotal porokeratosis that is seen on the penis and adjacent scrotal skin in young men in their third decade of life. Genitogluteal porokeratosis is usually pruritic and may be undiagnosed for several years as it does not resemble classical porokeratosis in many cases; however, a biopsy is diagnostic. In general, response of genital porokeratosis to any modality of treatment is disappointing. No malignant changes have hereto been reported in porokeratosis restricted to the genitogluteal region.

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