2019
DOI: 10.2215/cjn.09600818
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Pruritus and Patient Reported Outcomes in Non-Dialysis CKD

Abstract: Background and objectivesAmong patients on hemodialysis, pruritus has been associated with poorer mental and physical quality of life, sleep quality, depression, and mortality. We evaluated patients with nondialysis CKD to describe the prevalence of pruritus, identify associated factors, and investigate associations with patient-reported outcomes.Design, setting, participants, & measurementsUsing cross-sectional data from patient questionnaires in the CKD Outcomes and Practice Patterns Study (CKDopps), we … Show more

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Cited by 97 publications
(102 citation statements)
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“…The largest study of CKD-aP prevalence in patients with CKD, not yet on dialysis, comes from the CKD Outcomes and Practice Patterns Study (CKDopps). 7 CKDopps is an international, prospective, nephrology clinic-based cohort study of 5658 adult patients with stage 3-5 CKD (nondialysis) from the US, Brazil, and France. Demographic data, comorbid conditions, labs, medications, KDQOL-SF, and CES-D-short form are collected.…”
Section: Ckdmentioning
confidence: 99%
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“…The largest study of CKD-aP prevalence in patients with CKD, not yet on dialysis, comes from the CKD Outcomes and Practice Patterns Study (CKDopps). 7 CKDopps is an international, prospective, nephrology clinic-based cohort study of 5658 adult patients with stage 3-5 CKD (nondialysis) from the US, Brazil, and France. Demographic data, comorbid conditions, labs, medications, KDQOL-SF, and CES-D-short form are collected.…”
Section: Ckdmentioning
confidence: 99%
“…In a recent study of CKD-aP prevalence from this database, 67% of patients completed relevant survey data. 7 The studied population included 15% with stage 3a, 34% with stage 3b, 44% with stage 4, and 7% with stage-5 CKD. The prevalence of at least moderate pruritus was 24% (24% in Brazil, 29% in the US, and 23% in France), and of severe to extreme pruritus was 11% in Brazil, 13% in the US, and 10% in France.…”
Section: Ckdmentioning
confidence: 99%
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“…Chronic kidney disease (CKD) is associated with various cutaneous manifestations including pruritus, xerosis, pigmentation, yellow skin, perforating disorders, calciphylaxis, benign nodular calcification, porphyria cutanea tarda, pseudoporphyria, and nephrogenic systemic fibrosis (1)(2)(3). The most common manifestation, xerosis affects 66% to 72% (1,2), while pruritus affects 24% to 43% patients (1,2,4). Pruritus and xerosis often co-exist.…”
Section: Introductionmentioning
confidence: 99%
“…Non-dialysis patients with CKD stage 3-5 account for a relatively high proportion, the research and early intervention of these patients may reverse the progression to end-stage renal disease, thus, it has important clinical signi cance. The general clinical characteristics of non-dialysis patients have been widely studied [6][7][8]. However, to the best of our knowledge, there are few studies on the analysis of sarcopenia in non-dialysis patients with CKD stage 3-5.…”
Section: Introductionmentioning
confidence: 99%