Pruritus as a presenting sign of acquired immunodeficiency syndrome

Prevalence of skin diseases in Ibadan, Nigeria

“…Further studies are needed to identify possible causes in this environment. Possible causes documented elsewhere include hepatitis C, 25 hepatitis B, Helicobacter pylori , 32 helminthiasis, 33 and HIV infection 34 …”

British Association of Dermatologists’ guidelines for the investigation and management of generalized pruritus in adults without an underlying dermatosis, 2018

“…Pruritus due to cholestasis is associated with many viral infections, including hepatitis A, B, C and E . Pruritus typically occurs at a late stage of infection with HIV, although occasionally it may be a presenting feature . The degree of pruritus in HIV infection often correlates directly with the viral load and can be associated with eosinophilia .…”

Viral diseases

“…It is found in up to one-third of patients, and is an adverse prognostic factor. [807][808][809][810][811][812][813][814][815][816][817][818] Malignant melanoma and squamous cell carcinoma are examples of cutaneous malignancies that have a more aggressive course in patients with HIV infection. 804 The role of human herpesvirus-8 in its etiology is discussed elsewhere (see p. 619).…”