Pruritus in Chronic Kidney Disease

Azimi, Ehsan; Lerner, Ethan A.; Elmariah, Sarina B.

doi:10.1007/978-1-4939-2395-3_7

Cited by 3 publications

(6 citation statements)

References 71 publications

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“…There are no significant differences between hemodialysis patients and non-hemodialysis patients (Raspha et al, 2018;Charu and Anshul, 2020). The prevalence and intensity of uremic pruritus are not dependent on age, sex, ethnicity, and the duration of dialysis, although hemodialysis patients are more likely to experience it (Azimi, Lerner, and Elmariah, 2015). Uremic pruritus can be localized, generalized, episodic, or continuous (Galperin, Cronin, and Leslie, 2014; Charu *Correspondence:…”

Section: Nonspesific Manifestations Pruritusmentioning

confidence: 99%

“…Topical therapies for uremic pruritus include emollient, capsaicin cream, and tacrolimus. Regular application of emollients without scent and other additives to maintain the skin barrier's integrity, limit water loss, and reduce exposure to environmental irritants are the main treatment for uremic pruritus (Azimi, Lerner, and Elmariah, 2015). There are several systemic treatments for uremic pruritus, including UV light, opioid receptor agonists and antagonists, gabapentin, antihistamines, cromolyn sodium (CS), immunomodulators, activated charcoal, cholestyramine, ondancentrone, and intravenous erythropoietin (Gnanaserkan et al, 2020).…”

Section: Introductionmentioning

confidence: 99%

“…There are several systemic treatments for uremic pruritus, including UV light, opioid receptor agonists and antagonists, gabapentin, antihistamines, cromolyn sodium (CS), immunomodulators, activated charcoal, cholestyramine, ondancentrone, and intravenous erythropoietin (Gnanaserkan et al, 2020). Administration of cromolyn sodium (CS) orally (135 mg 3 times a day) and topical (4% cream) can reduce itching in hemodialysis patients (Azimi, Lerner, and Elmariah, 2015).…”

Section: Introductionmentioning

confidence: 99%

“…Therapeutic approaches of uremic pruritus (Source:Galperin, Cronin and Leslie, 2014;Azimi, Lerner and Elmariah, 2015) …”

mentioning

confidence: 99%

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Cutaneous Manifestations in End-Stage Renal Disease (ESRD)

Rahmatika,

Setyaningrum,

Sawitri

et al. 2024

Qanun Medika

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Skin can reflect systemic conditions due to abnormalities in internal organs, including kidney disorders. Cutaneous manifestations are common in patients with end-stage renal disease (ESRD). It can be severe and negatively impact a patient's quality of life. Clinicians can effectively manage ESRD by closely examining the patient's skin and nails, improving the patient's quality of life, and reducing mortality and morbidity. Clinicians can be more aware of ESRD by examining the patient's skin and nails closely so proper management can be performed and the patient's quality of life can be improved. This review aims to increase understanding of common cutaneous manifestations in ESRD for early recognition and better management. Cutaneous manifestations in ESRD are divided into specific and nonspecific manifestations. Specific manifestations include acquired perforating dermatosis (APD), bullous disease (porphyria cutanea tarda and pseudoporphyria), metastatic calcification (calcinosis cutis and calcific uremic arteriolopathy), and nephrogenic systemic fibrosis. Nonspecific manifestations include pruritus, xerosis, skin pigmentation changes, nail disorders, purpura, hair disorders, oral mucosal changes, skin infections, and other skin manifestations. These manifestations range from benign and asymptomatic to serious conditions that negatively impact life quality. In conclusion, Early detection and treatment of cutaneous manifestations in patients with ESRD are crucial for reducing morbidity and mortality and also improving patients' quality of life.

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Section: Nonspesific Manifestations Pruritusmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…Therapeutic approaches of uremic pruritus (Source:Galperin, Cronin and Leslie, 2014;Azimi, Lerner and Elmariah, 2015) …”

mentioning

confidence: 99%

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Cutaneous Manifestations in End-Stage Renal Disease (ESRD)

Rahmatika,

Setyaningrum,

Sawitri

et al. 2024

Qanun Medika

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“…The following criteria can help to diagnose uremic pruritus: (1) pruritus appearing immediately after dialysis or appearing at any time without being accompanied by other diseases that can actively trigger itching, (2) the patient had 3 or more episodes of itching in less than 2 weeks and symptoms occur several times a day with a duration of several minutes, and causing distress, (3) during six months, pruritus manifests in a regular pattern (Azimi, Lerner, and Elmariah, 2015).…”

Section: Introductionmentioning

confidence: 99%

Untitled

2024

Qanun Medika

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Traumatic severe brain injury is a fatal injury, with a mortality rate of up to 50%. About 1.5 million people experience severe brain injury in the United States. There are more than 50,000 deaths and 500,000 incidents of permanent neurological sequelae. About 85% of mortality occurs in the first 2 weeks after the injury. One complication of a severe brain injury is diabetes insipidus. There are no definitive data on the incidence of diabetes insipidus in patients with traumatic severe brain injury of Indonesia so far. In this case report, a male, 45 years old, was taken to the Emergency Installation (IRD) after experiencing a traffic accident 12 hours before being hospitalized. After surgery, the signs of diabetes insipidus was presented by polyuria of 300cc / hour urine production and 149mmol / L hypernatremia, although the immediate administration of desmopressin, the patients clinical and hemodynamic was not shown any improvements. The patient passed away in the days five of treatment in the Intensive Care Unit (ICU). The main treatments for diabetes insipidus in traumatic severe brain injury are adequate rehydration and administration of desmopressin. Adequate hypovolemic, polyuric and hypernatremia corrections are the keys to the successful treatment of diabetes insipidus. Diabetes insipidus in cases of brain injury requires complicated treatment. Therefore, in the case of being handled improperly, it can bring death.

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