PS-385a Clinical Outcomes After Bilevel Positive Airway Pressure (bipap) Treatment For Acute Asthma Exacerbations: Abstract PS-385a Table 1

Abstract

Aims To examine whether bilevel positive airway pressure (BiPAP) for children with acute asthma exacerbations not approaching respiratory failure (not meeting NIH and GINA guidelines for noninvasive ventilation) is associated with improved clinical outcomes. Methods We prospectively enrolled children 5-17 years with exacerbations not meeting respiratory failure guidelines for BiPAP use in a paediatric emergency department. We modelled propensity scores for BiPAP treatment then used propensity score matching to estimate the associations of BiPAP treatment with hospital admission; PICU admission; hospital length-of-stay; and time to Q4 hr albuterol as a metric of clinical improvement. Results Amongst 933 participants, median [IQR] age was 8.8 [6.9,11.2] years, male 61%, and African-American 59%. BiPAPtreated participants (n = 45) had similar demographic characteristics to BiPAP-untreated participants in the matched analysis and significantly greater likelihood of hospital and PICU admission (Table). Conclusions BiPAP treatment for paediatric patients with asthma exacerbations not meeting respiratory failure guidelines may be associated with greater resource utilisation without evidence of improved outcomes. Background and aims Inadequate physical activity (PA) is a common thread running through most public health problems across the world. PA declines during the lifespan, especially during adolescence. We studied the current status of PA of children in Anand, India in the age group 11-19 years. Methods Cross-sectional study using a self-reported Physical Activity Questionnaire (PAQ-A) which has consistently high validity and moderate reliability. It comprehensively captures the PA in last 7 days. Self-reported anthropometric data and sociodemographic data were also recorded. Of 3337 participants, anthropometric data was not reported in 784. Results Mean physical activity level (n = 3337) amongst adolescents was 2.62 (0.72 SD). In females it was 2.5670 (0 . 71 SD) and in males was 2.66 (0.73 SD). Correlating their PA with age, in females (n = 1410) correlation was -0.204 and in males (n = 1927) it was -.095. PA declines with age but in males not statistically significant. Lowest PA of 1.93 was reported from school (n = 231) where most students were appearing for boards within a year. Correlating PA with BMI (n = 2553), overall correlation was -0.116 showing insignificant correlation. Correlation of BMI with PA was -0.314 for an affluent school (n = 328). Most common physical activity was BICYCLING in males 55.9% and in females 51.7%. Swimming was practiced by 5.8%. Overall (n = 2617) 15.7% were overweight/obese (BMI > 23 for Indian population) In which 16.5% male and 14.8% female.