PS1:8 Anti-ro false-negatives detection through anti-ro52 kda and anti-ro60 kda analysis in systemic lupus erythematous patients

Abstract

ordered at the same time as the ANA, against the Choosing Wisely recommendation of 2013. There were only 22% of ANA that were required for a diagnosis. The 3 specilaties who ordered ANA the most were rheumatology, gastroenterology and the internal medicine (in descending order). The cost for the ANA that were not indicated is more than a thousand dollars. A total of 135 ANCA tests were included. There were 55.6% of ANCA that were ordered in line with the recommandations. However, 50.3% of ANCA were not required for the final diagnosis. Clinical remission of subjects with ANCA was predicted in 100% of cases, even before ordering the ANCA test for follow-up (negative predictive value). Conclusion These results show that the rate of ANA and ANCA tests ordered in line with the recommandations remains low. In the majority of cases, the two antibodies are not required for the final diagnosis. These orders have an important cost for the hospital that can be lowered by providing more education for professionals on avoiding unnecessary tests.