Purpose:
To screen the patients with monofocal intraocular lens (IOL) for incidence of unaided 20/40 and J5 for distance and near (pseudoaccommodation) and to find factors for pseudoaccommodation.
Settings:
University Hospitals Sussex NHS Foundation Trust, UK.
Design:
Prospective study
Methods:
This was a single-eye study (Clinicaltrials.gov: NCT04011696). At 3-9 months, refraction, uncorrected & best-corrected distance & uncorrected near LogMAR acuity, spherical equivalent (SEQ), mesopic pupil size (PS), total eye spherical (Z4
0), vertical coma (Z3
-1) aberrations, reading speed and smallest print size were assessed. Refractive astigmatism (RA) was classified as against-the-rule, with-the-rule, oblique and no astigmatism. Data on preoperative axial length (preopAL) and anterior chamber depth (preopACD) were collected.
Results:
29 patients (9.6%, 95% CI: 6.5-13.5) had pseudoaccommodation. In cases vs. controls, median SEQ, PS, total Z4
0, Z3
-1, reading speed, smallest print size, preopACD, preopAL were: -0.39 vs. 0.0Diopters; 3.62 vs. 4.10mm; 0.01 vs. 0.02µm; 0.018 vs. 0.022µm; 106 vs. 133wpm (words per minute); 0.30 vs. 0.50LogMAR; 2.94 vs. 3.13mm, 23.4 vs. 23.7mm, respectively. RA was not different between the groups. Univariate analysis revealed preopACD (OR=0.38, 95% CI=0.16-0.94, p=0.04), SEQ (OR=0.61, 95% CI=0.42-0.88, p=0.01), total Z4
0 (OR=0.0003, 95% CI=0.00-0.39, p=0.03) and PS (OR=0.39, 95% CI=0.22-0.69, p<0.041) to be significant. Whereas multivariate logistic regression identified: preopAL (OR=0.62, 95% CI=0.42-0.91, p=0.02), SEQ (OR=0.49, 95% CI=0.31-0.78, p=0.01), Z4
0 (OR=0.00, 95% CI=0.0-0.01, p=0.01) and PS (OR=0.41, 95% CI=0.23-0.75, p=0.01) to be significant.
Conclusions:
A combination of low myopic SEQ, lower Z4
0, shorter preop AL, and smaller PS increases the chances of pseudoaccommodation.