Pseudo-Meigs syndrome secondary to ovarian germ cell tumor

Pseudo-Meigs’ syndrome secondary to endodermal sinus tumour

“…A MEDLINE search of the English language literature using the terms: ' endodermal sinus tumour ' , ' yolk sac tumour ' , ' germ cell tumour ' , ' pseudo-Meigs ' syndrome ' and ' Meigs ' syndrome ' produced three reports of germ cell tumour associated with pseudo-Meigs ' syndrome (Table I) (Bridgewater and Rustin 1997;G ü cer et al 2005;Wolff et al 2005). Th e histological types reported have been endo- AFP, α -fetoprotein; β -hCG, β -human chorionic gonadotropin; FU, follow-up period; BEP CTx; chemotherapy with bleomycin, etoposide, and cisplatin for 3 -4 cycles; NED, no evidence of disease.…”

“…Malignancy from ovarian germ cell tumour, including endodermal sinus tumour, is a rare cause of this syndrome and only a few cases have been reported (Bridgewater and Rustin 1997;Wolff et al 2005). We report our clinical experience, review previously reported cases and discuss the diagnosis and treatment of pseudo-Meigs ' syndrome caused by endodermal sinus tumour.…”

Association of Pseudo-Meigs’ Syndrome with Struma Ovarii and High CA125 Mimicking Ovarian Malignancy

“…3,8,[12][13][14] Later, Rhoads and Terrell assigned the term Meigs' syndrome to this association. 13 Meigs' syndrome is rare, presenting fibromas with pleural effusion in 10-15% of cases and with ascites and pleural effusion in 1%.…”

“…3,8,[12][13][14] Later, Rhoads and Terrell assigned the term Meigs' syndrome to this association. 13 Meigs' syndrome is rare, presenting fibromas with pleural effusion in 10-15% of cases and with ascites and pleural effusion in 1%. 2,15 Other tumor types distinct from the fibroma, such as teratomas or uterine leiomyomas, are associated with Meigs' criteria, the preferred term being Pseudo-Meigs' syndrome (PMS).…”

“…2,8,15 This theory is supported by the rapid occurrence of pleural effusion after thoracocentesis and its identical biochemical composition in peritoneal as well as in pleural fluid. 13 It has recently been suggested that Vascular Endothelial Growth Factor (VEGF), Fibroblast Growth Factor (FGF), and Interleukin 6 (IL-6) are related with the production of ascites and hydrothorax, in that these possess properties of vascular permeability. 15 The elevation of Ca125 in the serum of postmenopausal women suggests that, in 80% of cases, the presence of ovarian cancer.…”