Pseudo-phosphorylation of essential light chains affects the functioning of skeletal muscle myosin

Yampolskaya, Daria S.; Kopylova, Galina V.; Shchepkin, Daniil V.; Nabiev, Salavat R.; Никитина, Л. В.; Walklate, Jonathan; Ziganshin, Rustam H.; Bershitsky, Sergey Y.; Geeves, Michael A.; Matyushenko, Alexander M.; Levitsky, Dmitrii I.

doi:10.1016/j.bpc.2022.106936

Biophysical Chemistry

2023

DOI: 10.1016/j.bpc.2022.106936

|View full text |Cite

Pseudo-phosphorylation of essential light chains affects the functioning of skeletal muscle myosin

Daria S. Yampolskaya

Galina V. Kopylova

Daniil V. Shchepkin

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 60 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Data-Independent Acquisition Method for In-Depth Proteomic Screening of Donkey Meat

Wang,

Qu,

Wang

et al. 2024

Agriculture

View full text Add to dashboard Cite

Donkey meat has gained popularity as an emerging meat product due to its superior nutritional value and distinctive flavor. Despite this, research on the molecular mechanisms that contribute to meat quality, particularly within the field of proteomics, remains limited. This study aimed to address this gap by utilizing the data-independent acquisition (DIA) technique to identify differentially expressed proteins (DEPs) in the gluteus superficialis (WG), longissimus thoracis (WLT), and semitendinosus (WS) muscles of donkeys. Our analysis revealed 189 and 384 DEPs in the WG/WLT and WS/WLT muscles, respectively. Several significant potential pathways, involving these DEPs, were found to be closely associated with donkey meat quality. These pathways include fatty acid biosynthesis, TGF-β signaling, FOXO signaling, mTOR signaling, oxidative phosphorylation, citrate cycle, alanine, aspartate, and glutamate metabolism, arginine biosynthesis, and valine, leucine, and isoleucine degradation. The identified DEPs and their regulated pathways were involved in regulating intramuscular fat deposition, protein metabolism, and amino acid metabolism in donkey muscles. These mechanisms have a direct impact on the physicochemical properties and flavor of donkey meat. Our findings contribute to a better understanding of the molecular processes influencing the quality of donkey meat. Additionally, the findings of our study may be influenced by the sample size. Therefore, further research with a larger sample is needed to provide a more comprehensive evaluation of meat quality.

show abstract

Data-Independent Acquisition Method for In-Depth Proteomic Screening of Donkey Meat

Wang,

Qu,

Wang

et al. 2024

Agriculture

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Pseudo-phosphorylation of essential light chains affects the functioning of skeletal muscle myosin

Cited by 1 publication

References 60 publications

Data-Independent Acquisition Method for In-Depth Proteomic Screening of Donkey Meat

Data-Independent Acquisition Method for In-Depth Proteomic Screening of Donkey Meat

Contact Info

Product

Resources

About