Pseudoexfoliation: High risk factors for zonule weakness and concurrent vitrectomy during phacoemulsification

Shingleton, Bradford J.; Marvin, Alicia C.; Heier, Jeffrey S.; O’Donoghue, Mark; Laul, Anupam; Wolff, Brian; Rowland, Anne P

doi:10.1016/j.jcrs.2010.02.014

Cited by 43 publications

(27 citation statements)

References 26 publications

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“…A study by Shingleton et al identified risk factors for zonular weakness defining the presence of any of the following as high-risk: preoperative phacodonesis, iridodonesis, or lens subluxation; those with anterior chamber depth or angle depth asymmetry within an eye or between eyes; and those with a complicated cataract extraction related to zonular weakness in the fellow eye. 48 This study showed that out of 1059 eyes, 11.5% were determined to be at high risk for zonular weakness. 48 A statistically significant difference was noted in high-risk eyes versus non high-risk-eyes requiring concurrent vitrectomy during phacoemulsification (15.6% of high-risk versus 2.0% of non-high-risk eyes; p50.00001).…”

Section: Comparison Of Complication Rates For Pseudoexfoliation and Nmentioning

confidence: 89%

Cataract Surgery in Pseudoexfoliation Syndrome

Sangal

Chen

2014

Seminars in Ophthalmology

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Pseudoexfoliation (PXF) syndrome is characterized by the deposition of distinctive fibrillar material in the anterior segment of the eye. It is an age-related process that is associated with open and narrow angle glaucomas and the formation of cataracts. Not only is PXF associated with the formation of dense nuclear cataracts, it is also well known that those presenting with PXF are at a higher risk of developing complications during, and even after, cataract surgery. Complications associated with cataract surgery in PXF can occur from poor pupillary dilation, zonular weakness leading to intraoperative or postoperative lens dislocation and vitreous loss, postoperative intraocular pressure (IOP) spikes potentiating glaucomatous damage, capsular phimosis, prolonged inflammation, and postoperative corneal decompensation. The surgeon should be prepared to encounter the various potential intraoperative and postoperative complications in eyes with pseudoexfoliation syndrome during cataract surgery. In this way, the surgeon can plan his/her surgical technique to help avoid surprises during cataract surgery and be prepared to manage the potential postoperative complications that can occur in pseudoexfoliation eyes.

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Section: Comparison Of Complication Rates For Pseudoexfoliation and Nmentioning

confidence: 89%

Cataract Surgery in Pseudoexfoliation Syndrome

Sangal

Chen

2014

Seminars in Ophthalmology

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“…This analysis is the most recent report in a series of more than 1200 eyes with PXF that had cataract surgery. [9][10][11] Patients were identified as having PXG based on slitlamp biomicroscopic examination; gonioscopy; dilated optic nerve head examination; visual field analysis; and history of treatment with topical glaucoma medications, previous glaucoma laser surgery, or both. Eyes with previous glaucoma filtration surgery were excluded from data analysis.…”

Section: Methodsmentioning

confidence: 99%

Combined cataract and trabeculectomy surgery in eyes with pseudoexfoliation glaucoma

Shingleton¹,

Wooler²,

Bourne³

et al. 2011

Journal of Cataract and Refractive Surgery

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“…[1][2][3][4][5] Such alterations can be a challenge for the cataract surgeon and are related to an increased risk for surgical and postsurgical complications. 6,7 Cataract, especially the nuclear subtype, is a frequent finding in PXF patients, and there is some evidence that defective antioxidant mechanisms and ocular ischemia increase the development of PXF.…”

mentioning

confidence: 99%