Pseudoexfoliation of the Lens Capsule and Liberation of Iris Pigment

Krause, U.; J, Helve; Forsius, Henrik

doi:10.1111/j.1755-3768.1973.tb08244.x

Cited by 61 publications

(36 citation statements)

References 12 publications

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“…Krause et al (1973) found the IOP to be higher in eyes with PEX when compared to PEX-negative eyes, similar results were obtained by Madden & Crowley (1982). Krause et al (1973) reported increased liberation of iris pigment in PEX-positive eyes implying that this might lead to trabecular blockage. Similar results were reported by Mapstone (1981).…”

supporting

confidence: 83%

Pigmentation of the anterior chamber angle in normal and pseudoexfoliative eyes

Rouhiainen

Teräsvirta²

1990

Acta Ophthalmologica

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supporting

confidence: 83%

Pigmentation of the anterior chamber angle in normal and pseudoexfoliative eyes

Rouhiainen

Teräsvirta²

1990

Acta Ophthalmologica

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“…The mean age of the responder group, 62.3 years, was a few years lower than the mean age of the total series. In the PE group, too, the mean Visual field Leydhecker 1973), similarly P E (Tarkkanen 1962;Aasved 1971;Krause 1973;Krause et al 1973;Forsius et al 1974 (Table I). Marked IOP elevations and concurrent liberation of profuse pigment in the aqueous were reported by Kristensen (1965Kristensen ( , 1968) during mydriasis test with sympathomimetics on some eyes with capsular glaucoma under treatment.…”

Section: Discussionmentioning

confidence: 80%

The Cyclopentolate Provocative Test in Suspected or Untreated Open‐angle Glaucoma

Valle

1976

Acta Ophthalmologica

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The mydriasis provocative test with 1% cyclopentolate (CPT) was performed on 218 patients with suspected or untreated open-angle glaucoma, on 431 eyes in all. Significant IOP elevations (larger than or equal to 8 mmHg) were demonstrated in 21 eyes of 18 patients. The present paper analyses the responder group and presents some other investigation results and clinical findings to throw additional light on the mechanism of IOP elevation in responders. The responders did not differ from the other patients of the material in age or sex. Patients with capsular glaucoma constituted the biggest group among the responders. 48% of the significant IOP elevations during CPT were encountered in eyes with pseudoexfoliation (PE) and open-angle glaucoma. A positive response during CPT was statistically significantly more common in PE eyes than in eyes without PE. Capsular glaucoma was diagnosed immediately or later in all PE eyes which displayed a larger than or equal to 5 mmHg IOP elevation during the CPT. In addition to the importance of pigment in PE eyes, PE material may play a certain role in the elevation of IOP . The mechanism of this role is not known. No correlation was established between the results of the water drinking test and the CPT. The mechanism that causes the elevation of IOP must be quite different in these two tests. Nor was a statistically significant difference observed in the incidence of cataract, the maximal variation of IOP in the 48-h tension curve, the occurrence of cupping of the optic disc or visual field defects between the responder and non-responder eyes in the glaucomatous group.

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“…For example, ES prevalences among Icelanders, Finns, and Lapps are greater than 20%. 32,34,56,57 One explanation may be that the extracellular deposits of ES represent a nucleation reaction 58 that is prone to develop at lower temperatures. While the temperature in the vascular iris may be close to the core body temperature, the temperatures in the avascular ocular segments, such the anterior chamber and lens, may be susceptible to ambient temperatures.…”

Section: Discussionmentioning

confidence: 99%