Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma

Abstract

BACKGROUNDPseudoexfoliation syndrome is a systemic disorder characterised by the deposition of white dandruff-like material within the anterior segment of the eye and other organs such as the heart, lungs and kidneys. The deposition of this material in the trabecular meshwork can result in aqueous flow obstruction, raised intraocular pressure and glaucoma. In fact, pseudoexfoliation glaucoma is the most common form of secondary open-angle glaucoma. In contrast to primary open-angle glaucoma, this disease runs a more aggressive clinical course with high intraocular pressure at onset, faster rates of progression, poor response to medical therapy and increased need for surgical intervention.