Pseudomalignant, nonneoplastic osseous soft-tissue tumors of the hand and foot.

Abstract

Seventeen patients with nonneoplastic osseous tumors in the soft tissues of the hands and feet were retrospectively studied. Three of the patients had a reliable history of trauma. Ten patients showed periosteal reaction associated with gradual formation of an osseous soft-tissue tumor, sometimes with a peripheral zone of bone density. Histologically (also radiographically), the lesions may be mistaken for malignant neoplasms such as osteosarcoma or parosteal osteosarcoma, especially when the pathologist does not receive representative material. In this series, malignancy was suspected in eight patients. Radiologic and pathologic criteria that may be helpful in the differential diagnosis of this lesion are presented. It is important that this nonneoplastic, benign, and self-limiting process in the hands and feet be recognized and treated accordingly. Local excision is adequate therapy in most cases, with little risk of local recurrence.

Magnetic resonance imaging of myositis ossificans: analysis of seven cases

“…Proposed etiologies include metaplasia of connective tissue cells and ossification of hematoma [3]. Conditions that appear similar radiographically and may be the same entity include pseudomalignant osseous tumor of the soft tissues, pseudomalignant myositis ossificans, and heterotopic ossification [6,8,10].…”

“…We elected to include cases with and without prior trauma since the histology and radiographic findings in these conditions are identical [6,10]. In fact, some authors believe that they are the same condition [6,10].…”

Fibro-Osseous Pseudotumor of the Thenar Eminence

“…These include: parosteal fasciitis, fasciitis ossificans, panniculitis ossificans, pseudo malignant osseous tumor of the soft tissues, and others. [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18] However, Dupree and Enzinger 1 were probably the first authors to label this benign but aggressive ossifying lesion mimicking malignant lesions as "fibro-osseous pseudotumor of the digit." Our report describes a characteristic tumor arising from the subcutaneous tissues of the thenar eminence with the classic radiographic and histopathologic appearance.…”

“…6,9,16 Thus the clinical differentiation of this tumor and other benign tumors such as fasciitis ossificans from malignant tumors that necessitate radical surgeries becomes apparent.…”

The diagnostic conundrum of Florid Reactive Periostitis: A case report and review of the literature

“…It can spontaneously resolve; be cured after excision, recur in an insidious pattern, or recur more aggressively with surmised aggravation from previous surgical trauma, as in our case. Many have had great success with excision, [3,6,7,10,[15][16][17] and while there are no reports of FRP being treated medically, spontaneous resolution has been documented. Misdiagnosis has occurred, which has led to unnecessary early radical amputations.…”