Pseudomesotheliomatous carcinoma of the lung with a distinct morphology, immunohistochemistry, and comparative genomic hybridization profile

Accuracy of pathological diagnosis of mesothelioma cases in Japan: Clinicopathological analysis of 382 cases

“…This is because some pleural mesotheliomas invade the pulmonary parenchyma and exhibit lepedic growth [7]. Sometimes pulmonary adenocarcinomas may grow along the visceral and/or parietal pleura, mimicking the growth of malignant pleural mesothelioma; this growth is detected clinically and/or radiologically and it is called "pseudomesotheliomatous adenocarcinoma" [17,18]. Over the last 10 years, many immunohistochemical markers for differentiating between epithelioid mesothelioma and pulmonary adenocarcinoma have been developed [10,[19][20][21][22][23][24].…”

Pleural Pseudomesotheliomatous Adenocarcinoma

“…Bu büyüme paternini gösteren tümörlerin çoğu periferik yerleşimli akciğer karsinomları olmakla birlikte; metastatik tü-mörler, primer plevral sarkomlar, lenfomalar, timik epitelyal tümörler de bu paterni gösterebilmekte-dir. 4 Plevral psödomezotelyomatöz karsinomlar nadir gözlenen tümörler olup, difüz plevral tümör-lerin %6'sını oluşturmaktadır. 3 Genellikle beş ve altıncı dekadlarda ortaya çıkmakta ve erkeklerde daha sık gözlenmektedir.…”

“…Tümör çapı genellikle 5 cm'nin üzerinde saptanmaktadır. [1][2][3][4][5][6] Olgumuzda da fissüre uzanan düzensiz-nodüler kalınlaşma, mediastinal-kostal ve diyafragmatik plevral kalın-laşma izlenmiştir.…”

Tumors of the Pleura

“…Over the past 25 years or so, several series of cases have been described, highlighting not only the similarities of this tumor to malignant mesothelioma but also providing the necessary tools to distinguish between these two conditions, in view of considerations regarding treatment and legal implications of the diagnosis. [84][85][86][87][88][89][90] Clinical Features…”