Pseudomonas aeruginosa and its sensitivity spectrum in chronic suppurative otitis media: A study from Garhwal hills of Uttarakhand State, India

Study of Aerobic Agents in Chronic Suppurative Otitis Media and their Sensitivity to Antibiotics in Ramadi City

“…In this study, P.aeruginosa isolates showed different rates of sensitivity towards the aminoglycoside antibiotics including Amikacin (71.4%) and Gentamicin (57,2%). These results were agreed with (Juyal et al, 2017) who reported sensitivity rates towards Amikacin (81.7%) and Gentamicin (29.3%) and disagreed with (Prasad et al, 2017) who reported sensitivity rate to Amikacin ( 65.7%) and Gentamicin (45.7%).Also, Aztreonam showed good effectiveness against P. aeruginosa isolates with a sensitivity rate (74.3%). This result was agreed with) who reported a sensitivity rate to Aztreonam (71.3%).…”

Prevalence and antibiogram of Pseudomonas aeruginosa in Chronic Suppurative Otitis Media (CSOM)

“…44,45 Pseudomonas aeruginosa has the ability to grow in damaged tissue with poor blood supply to the area which helps it to evade from host defense mechanism & from various antibiotics. 32,45 MDR being known in Pseudomonas aeruginosa, antibiotic susceptibility for them was tested by grouping the antibiotics into 6 groups. Aminoglycosides are the antibiotics which are active mainly against gram negative bacteria with mode of action being interfering in protein synthesis.…”

“…The identification was confirmed by standard biochemical tests. 26 31,32 So antibiotics tested were categorized into 6 classes. 1) Aminoglycosides -Amikacin, Gentamycin, Tobramycin 2) Cephalosporins -Cetazidime, Cefipime 3) Penicillin -Pipracillin, Pipracillin+Tazobactum 4) Carbapenems -Imipenem, Meropenem 5 Fluoroquinolones -Ciprofloxacin, Levoflaxacin 6) Monobactam -Aztreonam.…”

Pseudomonas aeruginosa: Diseases, Biofilm and Antibiotic Resistance

“…P. aeruginosa is one of the significant CSOM pathogens showing multiple resistances to the antibiotics with increase in frequency and make the treatment of patients extra difficult [43]. P. aeruginosa is a major organism result in CSOM, is one of the notorious pathogens with MDR attribute [44]. Also, P. aeruginosa is invading the human middle ear epithelial cells (HMEECs) as well as inducing cytoskeletal rearrangements [39], while the antibiotics resistance that is considered as worldwide health challenge is not a future threat anymore, yet current problem to all clinical setting's facets.…”