Pseudomonas oryzihabitans Infected Total Hip Arthroplasty

Abstract

Pseudomonas oryzihabitans is a saprophytic gram-negative microorganism usually found in damp environments, only occasionally responsible for human pathology. Infection mainly occurs in malnourished, immunocompromised individuals with indwelling catheters. There is no previous published record of infection after joint arthroplasty. To enhance the literature, in this article we report a patient with a Pseudomonas oryzihabitans infected total hip arthroplasty, and discuss the diagnosis and management of this unusual infection.

The first report of Pseudomonas oryzihabitansin infection in a patient with hidradenitis suppurativa

“…Our patient was treated by piperacillin/tazobactam, imipenem, and ceftazidime. The former reports confirmed that imipenem and ciprofloxacin are the first therapeutic choices for P oryzihabitant infection …”

“…We reported the first case of skin infection of P oryzihabitans in a patient with hidradenitis suppurativa; we isolated the bacterium as monomicrobial infection in which its potential pathogenicity can be approved in the case of cutaneous infection. Patients with diabetes mellitus are susceptible to various infections caused by opportunistic agents; review of the literatures shows that patients with immune deficiency are provided with the best condition to be infected with P oryzihabitans …”

“…Patients with diabetes mellitus are susceptible to various infections caused by opportunistic agents; review of the literatures shows that patients with immune deficiency are provided with the best condition to be infected with P oryzihabitans. 4,5,12 Pseudomonas oryzihabitans is an infrequent opportunistic pathogen not identified at the species level by phenotyping test, because of different phenotyping results in their strains. Moreover, P oryzihabitans's signature 16S rRNA gene sequence is unique; therefore, molecular techniques such as 16S rRNA sequencing are recommended for accurate identification of the bacterium in clinical specimens.…”

“…P oryzihabitans is a saprophytic bacteruim that lives freely in environmental resources such as soil, rice paddles, medical equipment, or hospital wash‐hand basin . Primarily, P oryzihabitants was not referred to as a pathogenic bacterium until 1970s when the first case of bacteremia was reported by Hellou et al Nowadays, this bacterium is known as a pathogenic bacterium isolated from human infections such as wound and soft tissue infections, septicemia, hip infection, prosthetic valve endocarditis, peritonitis, meningitis, abscesses, pneumonia, and urinary tract infections . According to previous reports, P oryzihabitans can be considered as a nosocomial agent associating with several outbreaks .…”

“…1,2 Primarily, P oryzihabitants was not referred to as a pathogenic bacterium until 1970s when the first case of bacteremia was reported by Hellou et al 3 Nowadays, this bacterium is known as a pathogenic bacterium isolated from human infections such as wound and soft tissue infections, septicemia, hip infection, prosthetic valve endocarditis, peritonitis, meningitis, abscesses, pneumonia, and urinary tract infections. 4,5 According to previous reports, P oryzihabitans can be considered as a nosocomial agent associating with several outbreaks. 6,7 Given that literatures, immune-disorder patients are exposed to be infected with P oryzihabitans more than the others.…”