Pseudoobstruction of the colon

Bachulis, Ben L.; Smith, Paul Edmund

doi:10.1016/0002-9610(78)90202-7

Cited by 104 publications

(48 citation statements)

References 16 publications

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“…Conservative management is successful as the primary treatment in the majority of patients. [14][15][16][17][18][19] Sloyer et al reported 25 cancer patients with ACPO (mostly nongastrointestinal malignancies). 14 The mean cecal diameter was 11.7 cm (range 9-18 cm).…”

Section: Supportive Therapymentioning

confidence: 99%

Acute colonic pseudo-obstruction

Saunders

2007

Best Practice & Research Clinical Gastroenterology

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Section: Supportive Therapymentioning

confidence: 99%

Acute colonic pseudo-obstruction

Saunders

2007

Best Practice & Research Clinical Gastroenterology

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“…The clinical and radiologic picture closely resembles mechanical obstruction of the large bowel (1).…”

Section: Discussionmentioning

confidence: 95%

Caecal Perforation Secondary to Idiopathic Caecal Dilatation– An Interesting Case

Reddy¹,

Karigalan²

2012

jemds

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ABSTRACT:Acute pseudo-obstruction of the colon(Ogilvie's syndrome) involves acute colonic distension without mechanical obstruction or stercoroma in a previously healthy colon. Colonic pseudo-obstruction can be diffuse or segmental. The cause for idiopathic colon dilatation is not known. Caecal rupture due to colonic ileus is rare and has a mortality rate of 43 per cent. We report a case of idiopathic caecal dilatation causing caecal perforation. On emergency laparotomy, caecal perforation secondary to segmental caecal dilatation without organic obstruction was found in this patient.

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“…18 There have since been numerous theories regarding the etiology of the syndrome, including loss of sympathetic stimulation, prostaglandin abnormalities, transient ischemia, mechanical air-fluid lock of the bowel, diminished parasympathetic stimulation, and/or autonomic imbalance. 2,3,9,19,23 While the underlying pathophysiology remains unclear, the syndrome is characterized by decreased gastrointestinal motility with massive colonic dilation in the absence of mechanical obstruction and with limited small bowel involvement. This distinguishes the syndrome from severe postoperative adynamic ileus, which affects the small bowel and does not respond well to neostigmine.…”

Section: Discussionmentioning

confidence: 99%

Ogilvie's syndrome after pediatric spinal deformity surgery: successful treatment with neostigmine

Hooten¹,

Oliveria²,

Larson

et al. 2014

PED

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Ogilvie's syndrome is a rare and potentially fatal disease that can easily be mistaken for postoperative ileus. Also known as acute colonic pseudo-obstruction, early recognition and diagnosis of the syndrome allows for treatment prior to bowel perforation and requisite abdominal surgery. The authors report a case of Ogilvie's syndrome following spinal deformity correction and tethered cord release in an adolescent who presented with acute abdominal distension, nausea, and vomiting on postoperative Day 0. The patient was initially diagnosed with adynamic ileus and treated conservatively with bowel rest, reduction in narcotic dosage, and a regimen of stool softeners, laxatives, and enemas. Despite this treatment, her clinical course failed to improve, and she demonstrated significant colonic distension radiographically. Intravenous neostigmine was administered as a bolus with a rapid and dramatic response. This case is the first reported instance of neostigmine use for Ogilvie's syndrome treatment following a pediatric neurosurgical operation.

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Pseudoobstruction of the colon

Cited by 104 publications

References 16 publications

Acute colonic pseudo-obstruction

Acute colonic pseudo-obstruction

Caecal Perforation Secondary to Idiopathic Caecal Dilatation– An Interesting Case

Ogilvie's syndrome after pediatric spinal deformity surgery: successful treatment with neostigmine

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