Pseudosymmetry in a cyclopalladated compound

Abstract

The enantiomerically pure title complex, [SP-4-4]-(R)-[2-(1-aminoethyl)phenyl-κ(2)C(1),N]chlorido(quinoline-κN)palladium(II) acetone hemisolvate, [Pd(C(8)H(10)N)Cl(C(9)H(7)N)]·0.5C(3)H(6)O, crystallizes with four molecules of the organopalladium complex and two molecules of acetone in the asymmetric unit. This corresponds to a discrete hydrogen-bonded aggregate and to the content of the unit cell in the space group P1. Pronounced pseudo-inversion symmetry relates pairs of these objects in the asymmetric unit.

Crystal structure of hexakis(dimethyl sulfoxide-κO)cobalt(II) bis[trichlorido(quinoline-κN)cobaltate(II)]

“…Quinoline-based molecules have shown significant promise in the development of clinically viable anti-cancer drugs (Afzal et al, 2015). Metal complexes containing quinoline include: (i) square-planar palladium-and platinum-quinoline compounds, such as trans-[Pd(II)Cl 2 (quinoline) 2 ], cis-[Pt(II)Cl 2 (quinoline) 2 ] and trans-[Pd(II)(N 3 ) 2 (quinoline) 2 ] (Ha, 2012;Klapö tke et al, 2000;Raven et al, 2012;Davies et al, 2001), as well as (ii) tetrahedral cobalt-, nickel-and zinc-quinoline compounds, of the form [M II Cl 2 (quinoline) 2 ] (Golic & Mirceva, 1988). Interestingly, despite the fact that the interaction of dimethyl sulfoxide (Me 2 SO) with metal ions has been studied for many years (Cotton & Francis, 1960), metal compounds that incorporate both coordinated quinoline and Me 2 SO are rare, as illustrated by the fact that only one structurally characterized example is listed in the Cambridge Structural Database (Groom et al, 2016), Zn(O 2 CC 6 H 4 -C 2 HN 3 CO 2 CH 3 ) 2 Á(quinoline)ÁMe 2 SO (Ma et al, 2012).…”