Pseudotumor inflamatorio: diagnóstico diferencial de los tumores del IV ventrículo

Olivares-Romero, J; Serrano-Castro, Pedro J.; Roig, J.M. Saladié; Guardado-Santervás, P; Peralta-Labrador, J I; Goberna-Ortiz, E

doi:10.33588/rn.3201.2000050

Cited by 4 publications

(4 citation statements)

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“…XG are benign tumors that occur throughout the body, however primary involvement of XG in the CNS is rare. [4,5] Blumer described the first known case of choroid plexus XG in 1900, naming it cholestomatous endothelioma.…”

Section: Discussionmentioning

confidence: 99%

Case Presentation: Unusual Association Between Possible Bilateral Intraventricular Xanthogranulomas, Postero-inferior Cerebellar Artery Aneurysm and Thrombophilia

Andone¹,

Romaniuc²,

Bajkó

et al. 2018

Acta Medica Marisiensis

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Introduction: Xanthogranulomas are rare, benign, usually asymptomatic, cutaneous tumors most frequently seen in children (juvenile xanthogranulomas). Some lesions can be found accidentally at randomly performed cerebral computer tomography (CT) or magnetic resonance imaging (MRI) or even on autopsy.Case report: We present the case of a 44 year-old woman, known with a thrombophilic disorder (PAI-1 gene mutation, MTHFR C677T and A1298C) on chronic anticoagulant treatment. The onset of symptoms was in 2010, when she presented paresthesia and lower limbs weakness. Two years later the patient presents with severe intermittent headache and left hemicrania and a cerebral angio-MRI is performed showing a left postero-inferior cerebellar artery aneurysm and two choroid plexus intraventricular masses in the lateral ventricles. The patient developed a new symptom, dysarthria in 2014 and in 2015 has multiple episodes of loss of consciousness, interpreted as epileptic seizures. Routine blood tests were within normal range, except for a high cholesterol level. The patient was tested for autoimmune, infectious, endocrine and metabolic diseases that were negative. Surgical treatment and biopsy from the lesion was proposed, however the patient refused both procedures.Conclusions: There is an association between xanthogranulomas localization and the choroid plexus, the most frequent CNS origin being in the trigon of the lateral ventricle. Our case does not resemble with any other case published, mostly because the unusual presentation, symptomatology and the association between xanthogranulomas, thrombophilia and postero-inferior cerebellar artery aneurysm which were never reported before in other cases of xanthogranulomas from the literature.

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Section: Discussionmentioning

confidence: 99%

Case Presentation: Unusual Association Between Possible Bilateral Intraventricular Xanthogranulomas, Postero-inferior Cerebellar Artery Aneurysm and Thrombophilia

Andone¹,

Romaniuc²,

Bajkó

et al. 2018

Acta Medica Marisiensis

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“…The current literature review for the 46 cases revealed that the age at presentation ranged between 1.5-to 80 years of age (average: 25-years) with 50% occurrence under the age of 20, with male predominance of 2:1. There was also an unusual racial predilection; 7 were black [16,17,30,36,39,40] ; 7 were oriental [19,23,32,35,38,47] ; 5 were Hispanic [21,22,24,27,50] ; 3 were Indian [34,42,51] ; one was Native American [18] ; with no reports coming from Arab region. Although there is a high possibility that those with no description of their race were Caucasian, only 3 were clearly noted to be of white race [7,28,30,37,41,[43][44][45][46]49] .…”

Section: Discussionmentioning

confidence: 99%

“…Hyperostosis in the case reported by Mirra et al, was due to the coexisting frontal meningioma [36] . Twenty-five patients had detailed description of the preoperative MRI scan, among these the PCGs appeared as iso-to hypointense on T1 and hypointense on T2 MRI scans [7,20,25,30,33,35,44,[46][47][48][49][50][51] . The low signal intensity has been suggested to result from the calcifications, the presence of free radicals produced by active inflammatory cells as well as the numerous small hemorrhages and the fibrous components.…”

Section: Radiological Diagnosismentioning

confidence: 99%

“…Three cases were exceptional: the insular lesion in a 60-year-old man without any dural attachment and with significant perilesional edema was thought to represent a secondary brain tumor [25] . The radiological diagnosis of 2 cases with 4th ventricular PCGs was thought to be medulloblastoma, ependymoma or astrocytoma [31,50] . Aozasa et al, suspected that their case of a 76-year-old male with hypodense and peripherally enhancing suprasellar mass was either a craniopharyngioma or a pituitary adenoma [19] .…”

Section: Radiological Diagnosismentioning

confidence: 99%

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Plasma Cell Granulomas of the Central Nervous System

Baeesa

2006

med

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Plasma cell granulomas of the central nervous system are rare benign forms of inflammatory pseudotumor of unknown etiology. They are often characterized by nonneoplastic proliferation of plasma cells and mimicking neoplastic processes. The author describes the management of six patients with histological proven plasma cell granulomas presented primarily with headache. Three were males with their age ranged from 9 to 43 years and a mean follow up of 40 months. The preoperative imaging studies revealed 3 cases located in the cerebral convexity and 3 were located in the posterior fossa region. Craniotomy was performed in 5 patients and in three patients complete resection was achieved. The resection was subtotal in 2 patients and they received postoperative steroids and radiation therapy. Complete resolution of the residual lesion was observed in one, and in another, the residual lesion remained stable during follow-up. One patient with infiltrating petroclival lesions had image-guided trans-nasal biopsy followed by radiation therapy with partial response. The author reviewed the literature of this rare entity and identified 46 reported cases of plasma cell granulomas. The clinicopathological and radiological findings, and the differential diagnoses were discussed and the management was outlined.

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