Psoríase de von Zumbusch

Abstract

A disorder of unknown origin, psoriasis is characterized by erythemato-squamous eruption. Amongst its clinical and morphologic presentations there is acute generalized pustular psoriasis, termed the von Zumbusch variant, accompanied by generalized toxicity. It is often triggered when stopping steroids, in unstable psoriasis patients. Case report of atypical development that began during prednisone use; complete clearing of lesions and symptoms was achieved with 35 days of acitretin.

Generalized pustular psoriasis induced by systemic steroid dose reduction

“…2 Among the aggravating factors the infections, sunburns, use of certain medications (lithium, salicylates, tar, chloroquine and beta-blockers) and, especially, the use and later interruption in the use of systemic corticosteroids stand out. 3 In this work, the case of a patient who developed grave symptoms of GPP while reducing the dose of prednisone is reported.…”

A painful rash

“…Treatment usually includes the use of oral retinoids. Although the etiology is unknown, generalized pustular psoriasis can be triggered by the cessation of oral steroids, 1 as was probably the case with this patient.…”

“…The patient's foot with a pustular rash.Diagnostic ChallengeA painful rash Jeremy M. Rose, MD*; Ryan Sustrik, MD 3 ; Shane Silver, MD 4 ; Anthony Herd, MD1 …”

Severe hypocalcaemia‐related pustular psoriasis in an 83‐year‐old woman with Fahr's syndrome: a case report

“…Generalized pustular psoriasis (GPP), also known as von Zumbusch psoriasis, is an acute rare and severe presentation of psoriasis with skin lesions accompanied by general symptoms such as fever and chills. 5 Fahr's syndrome, also known as bilateral striopallidodendate calcinosis, is a rare (and often asymptomatic) neurological disorder defined by the presence of bilateral intracranial calcifications that can be related to hypocalcaemia. 4 To our knowledge, this is the second report of severe hypocalcaemia associated with GPP and Fahr's syndrome.…”

“…3 We have previously showed mTOR involvement in some of the most common inflammatory dermatoses, including HS. 4,5 Recently, biologics are emerging in the…”