Psoriatic arthritis mutilans (PAM) in the Nordic countries: demographics and disease status. The Nordic PAM study

Abstract

PAM in the Nordic countries has a low prevalence, with only three to five cases per million inhabitants. The majority of the patients present with mild skin disease.

Disease activity in and quality of life of patients with psoriatic arthritis mutilans: the Nordic PAM Study

“…We have previously reported inclusion and exclusion criteria for the Nordic PAM Study, as well as demographics and disease settings in 59 patients with PAM (14). The objectives of the present study are to report the quality of life of PAM sufferers in the Nordic countries, and to describe effects of the disease on functional capacity and social life.…”

“…In an early Swedish PsA cohort (n = 334) with a 10 year follow-up, none of the patients developed PAM (16, personal communication T Husmark, 2014). In our recent epidemiological study in the Nordic population, the prevalence of PAM was found to be only 3.9 per million inhabitants (14). Occasionally, arthritis mutilans can also be associated with other severe arthritic diseases, e.g.…”

“…Subsequent categorization of PsA suggested subdivision into two main groups, with or without axial involvement (12), where coexisting polyarthritis predicted an unfavourable outcome (13). The most deforming variant of PsA is PAM, with a prevalence of about 5% according to Moll and Wright (11), even though this phenotype seems rare nowadays (14). Nevertheless, the prevalence of PAM in one cohort of established PsA was reported to reach 21% (15).…”

Psoriatic Arthritis Mutilans: Case Series and Literature Review

“…Only studies in which clinical data of patients with AM were specifically reported were extracted. Full articles of all relevant studies were retrieved, and manual searches of reference lists from these articles were performed, identifying 14 suitable studies ( Figure 2) 3,4,5,6,7,8,9,10,11,12,13,14,15,16 . Including our series, a total of 120 patients with AM are described ( Table 1).…”

Clinical and anamnestic criteria of the progression of psoriasis

“…Данные о превалировании мужчин среди больных ПсА подтверждают результаты исследова-ния испанской популяции (среди больных ПсА мужчин 57,2%, женщин -43,8%) и популяции пе-руанских островов (65%) [25,26]. Среди европеоид-ных популяций (норвежской, исландской) распро-страненность ПсА у женщин и мужчин одинакова [27].…”