2022
DOI: 10.1093/jas/skac247.528
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PSXV-10 Poor Maternal Nutrition Impacts Mrna Expression of Epigenetic Factors in ram Offspring Liver

Abstract: Poor maternal nutrition (over- and restricted-feeding) alters growth and metabolism in offspring after birth; however, the mechanisms are not well understood. Epigenetics, the heritable changes in gene expression without altering the DNA sequence, is a possible mechanism. We hypothesized that mRNA expression of epigenetic factors in livers of male offspring would be altered as a result of poor maternal diet during gestation. Multiparous Dorset ewes (n = 46) pregnant with twins were fed 100%, 60% or 140% of NRC… Show more

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