Psychiatric and somatic comorbidities are negatively associated with quality of life in physically ill patients

Baumeister, Harald; Balke, Katrin; Härter, Martin

doi:10.1016/j.jclinepi.2005.03.011

Cited by 128 publications

(86 citation statements)

References 72 publications

(232 reference statements)

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“…This finding is in line with recent reviews on the association of somatic or psychiatric comorbidities and quality of life in patients with chronic somatic diseases. 34,35 Although comorbid somatic diseases primarily aggravate physical aspects of quality of life, psychiatric comorbidities lower both mental and physical aspects. Perhaps this lowered perception of quality of life in obese individuals with comorbid mental disorders leads to an increased utilization of healthcare provisions.…”

Section: Discussionmentioning

confidence: 99%

Mental disorders in patients with obesity in comparison with healthy probands

2007

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Objective: Findings concerning the association of obesity and mental disorders are inconsistent. The present epidemiological study investigates adjusted 4-week, 12-month, and lifetime prevalence rates of mental disorders in obese individuals compared with physically healthy probands and overweight individuals. Correlates of the associations are examined. Methods: Prevalence rates were calculated from two large epidemiological surveys from both the general population of Germany and inpatient centers. The surveys investigated subjects with obesity (n ¼ 910) and overweight (n ¼ 1550), as well as physically healthy probands (n ¼ 495). The prevalence rates were based on the Munich-composite international diagnostic interview, a standardized interview for the assessment of mental disorders. Correlates of mental disorders in obese individuals were assessed using self-report questionnaires and medical examinations. Results: The adjusted odds ratios (OR) of obese inpatients and obese patients from the general population were significantly elevated in comparison with healthy probands for the 4-week (OR: 2.2; 2.3), 12-month (OR: 1.8; 2.7) and lifetime (OR: 1.4; 2.0) periods. Prevalence rates of overweight individuals were below those of obese individuals. Mood, anxiety and somatoform disorders were most frequent. In particular, sex, marital status and comorbid musculoskeletal diseases proved to be correlates of an increased risk for mental disorders in obese individuals. The presence of comorbid mental disorders was associated with significantly increased health care use and lower quality of life. Conclusions: There is a strong relationship between obesity and mental disorders. A future task is to improve care of mental disorders in patients with obesity.

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Section: Discussionmentioning

confidence: 99%

Mental disorders in patients with obesity in comparison with healthy probands

2007

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“…Patient education, routine monitoring of blood glucose and prevention of diabetes complications are just some of the common challenges in clinical practice. Mental disorders (mainly depression) in patients with diabetes were found to be associated with a significant impairment of glycaemic control [2], quality of life [3] and adherence to treatment regimen [4,5], thus affecting management of the disease. However, data on healthcare costs in patients with diabetes with comorbid mental disorders are confusing and partly inconsistent.…”

Section: Introductionmentioning

confidence: 99%

Healthcare costs in patients with diabetes mellitus and comorbid mental disorders—a systematic review

2010

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Aims/hypothesis We systematically reviewed the impact of comorbid mental disorders on healthcare costs in persons with diabetes. Method We conducted a comprehensive search for studies investigating adult persons (≥18 years old) with diabetes mellitus. All studies that allowed comparison of healthcare costs between diabetic patients with mental disorders and those without were included. Results We identified 4,273 potentially relevant articles from a comprehensive database search. Of these, 31 primary studies (39 publications) fulfilled inclusion criteria, of which 27 examined comorbid depression. Hospitalisation rates and hospitalisation costs, frequency and costs of outpatient visits, emergency department visits, medication costs and total healthcare costs were mainly increased with small to moderate effect sizes in patients with diabetes and comorbid mental disorders compared with diabetic patients without such problems. Frequency (standardised mean difference [SMD]=0.35-1.26) and costs (SMD= 0.33-0.85) of mental health specialist visits were increased in the group with mental health comorbidity. Results regarding diabetes-related preventive services were inconsistent but point to a reduced utilisation rate in diabetic patients with comorbid mental disorders. Statistical heterogeneity between studies was high (I 2 range 64-98%).Pooled overall effects are therefore not reported. Studies included differ substantially regarding sample selection, assessment of diabetes and comorbid mental disorders, as well as in assessment of cost variables. Conclusions/interpretation In light of the increased healthcare costs and inadequate use of preventive services, comorbid mental disorders in patients with diabetes must become a major focus of diabetes healthcare and research.

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“…A presença de dor e o uso de terapias antineoplásicas (interferon, quimioterapia) são fatores de risco, além de dificultarem a identificação da depressão, que ainda permanece um desafio para o médico que atende pacientes com câncer. A depressão, por sua vez, aumenta o uso de serviços de saúde mental, interfere negativamente com a adesão aos tratamentos do câncer e com a qualidade de vida dos pacientes 5,6 . Os benefícios do uso de antidepressivos na depressão em pacientes com câncer estão bem estabelecidos na literatura.…”

Section: Introductionunclassified

Depressão e câncer

Bottino¹,

Fráguas

Gattaz

2009

Rev. psiquiatr. clín.

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ResumoA depressão é o transtorno psiquiátrico mais comum em pacientes com câncer, com prevalências variando de 22% a 29%. Essa variabilidade está associada a sítios do tumor, estágio clínico, dor, funcionamento físico limitado, além da existência de suporte social. A depressão associa-se a um pior prognóstico e aumento da mortalidade pelo câncer. Síndromes depressivas podem ser uma consequência das terapias antineoplásicas, como ocorre em 21% a 58% dos pacientes recebendo interferon-alfa. Sentimentos de tristeza e desespero podem inibir a procura de cuidado pelos pacientes, dificultando o reconhecimento da depressão. O tratamento com antidepressivos é efetivo e melhora a adesão aos tratamentos do câncer, reduzindo efeitos adversos como náusea, dor e fadiga. Em pacientes com câncer, tratamento prévio com antidepressivos pode minimizar sintomas depressivos induzidos por interferon-alfa. O tratamento com antidepressivos parece ser uma estratégia efetiva para prevenir o desenvolvimento da depressão induzida por interferon-alfa. Intervenções psicossociais, como técnicas de relaxamento, terapia individual e em grupo, também podem ser utilizadas na redução dos sintomas depressivos e de estresse em pacientes com câncer. Bottino SMB, et al. / Rev Psiq Clín. 2009;36(3):109-15Palavras-chave: Depressão, câncer, diagnóstico, tratamento. AbstractDepression is the most common psychiatric disorder in patients with cancer, with prevalence rates ranging from 22% to 29%. This variability is associated to cancer sites, clinical stages, pain, limited physical functioning, beyond the existence of social support. Depression is associated to poorer prognosis and higher cancer mortality. Depressive syndromes can be a consequence of the antineoplasic therapies, as occurs in 21% to 58% of the patients treated with alfa-interferon. Sadness and desperation can inhibit the search for care by the patients, and difficult depression recognition. Antidepressant treatment is effective, and improve the adherence to cancer treatments, reducing side effects as nausea, pain and fatigue. In cancer patients, pretreatment with antidepressants seems to minimize depressive symptoms induced by interferon-alfa. Psychosocial interventions as relaxing techniques, group and individual psychotherapies can also be applied to reduce depressive and stress symptoms in patients with cancer.Bottino SMB, et al. / Rev Psiq Clín. 2009;36(3):109-15

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Psychiatric and somatic comorbidities are negatively associated with quality of life in physically ill patients

Cited by 128 publications

References 72 publications

Mental disorders in patients with obesity in comparison with healthy probands

Mental disorders in patients with obesity in comparison with healthy probands

Healthcare costs in patients with diabetes mellitus and comorbid mental disorders—a systematic review

Depressão e câncer

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