After 3 decades of intensive research, there is still confusion about the nature and reliability of relations between psychological factors and coronary heart disease (CHD). A meta-analysis, or quantitative review, was performed to integrate and organize the results of studies that investigated certain personality variables in relation to CHD. The personality variables included were anger, hostility, aggression, depression, extroversion, anxiety, Type A, and the major components of Type A. The meta-analytic framework helps focus attention on issues needing clarification. The results indicate that modest but reliable associations exist between some of the personality variables and CHD. The strongest associations were found for Type A and, surprisingly, for depression, but anger/hostility/ aggression and anxiety also related reliably to CHD. The Structured Interview diagnosis of Type A was shown to be clearly superior to the Jenkins Activity Survey as a predictor of CHD. The Type A-CHD relation was smaller in prospective than in cross-sectional studies and smaller in recent than in less recent studies. This review also revealed that information about the interrelations of personality predictors of CHD is sorely needed. The picture of coronary-proneness revealed by this review is not one of a hurried, impatient workaholic but instead is one of a person with one or more negative emotions. We suggest that the concept of the coronary-prone personality and its associated research be broadened to encompass psychological attributes in addition to those associated with Type A behavior and narrowed to eliminate those components that the accumulated evidence shows to be unimportant.Understanding the relation between psychological factors and heart disease has proved to be a difficult task, hampered by the weaknesses of vague constructs and correlational research designs. After nearly a century of speculation and 3 decades of intensive research, the nature of the relation between psychological factors and coronary heart disease (CHD) is still unclear.Yet because CHD is such a serious problem, accounting for about a third of all deaths in the United States, most would agree that the issue deserves continued investigation and review.Most of the research conducted in search of a coronary-prone personality-a style of behaving and coping that leads to coronary artery damage-has focused on the Type A behavior pattern (TABP), a collection of behaviors that seems predictive of clinically apparent CHD (Cooper, Detre, & Weiss, 1981; Dembroski, Weiss, Shields, Haynes, & Feinleib, 1978). As described by its discoverers, the TABP refers broadly to the behavior pattern of any person who is involved in an aggressive and incessant struggle to achieve more and more in less and less time (e.g., M. Friedman & Rosenman, 1974;Rosenman, 1978). The major elements of the behavior pattern are competitive achievement striving, a sense of time urgency and impatience, aggressiveness, and easily aroused hostility. One major question of this review is whe...