Psychiatric Diagnoses and Weight Loss Among Adolescents Receiving Sleeve Gastrectomy

Mackey, Eleanor R.; Wang, Jichuan; Harrington, Chloe; Nadler, Evan P.

doi:10.1542/peds.2017-3432

Cited by 23 publications

(18 citation statements)

References 46 publications

(38 reference statements)

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“…The three available studies on the prevalence of ADHD in adolescents seeking MBS reported widely variable results. An Israeli study reported an ADHD prevalence of 28.6% in this population, 9 one American study reported only a 6% prevalence of ADHD, 10 and the other American study reported that 21% of adolescent MBS patients met the criteria for an ADHD diagnosis 11 …”

Section: Introductionmentioning

confidence: 84%

“…An Israeli study reported an ADHD prevalence of 28.6% in this population, 9 one American study reported only a 6% prevalence of ADHD, 10 and the other American study reported that 21% of adolescent MBS patients met the criteria for an ADHD diagnosis. 11 ADHD presents in three different ways: combined presentation (deficits in both attention and hyperactivity-impulsivity), predominantly inattentive presentation, previously referred to as attention-deficit disorder (ADD) and predominantly hyperactive/ impulsive presentation. 12 It is not known which, if any, of these presentations are more common in adolescents with severe obesity seeking MBS.…”

Section: Introductionmentioning

confidence: 99%

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High prevalence of neurodevelopmental problems in adolescents eligible for bariatric surgery for severe obesity

et al. 2020

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Aim To assess the prevalence of neurodevelopmental problems in adolescents with severe obesity and their associations with binge eating and depression. Methods Data were collected at inclusion in a randomised study of bariatric surgery in 48 adolescents (73% girls; mean age 15.7 ± 1.0 years; mean body mass index 42.6 ± 5.2 kg/m2). Parents completed questionnaires assessing their adolescents’ symptoms of attention‐deficit/hyperactivity disorder and autism spectrum disorder and reported earlier diagnoses. Patients answered self‐report questionnaires on binge eating and depressive symptoms. Results The parents of 26/48 adolescents (54%) reported scores above cut‐off for symptoms of the targeted disorders in their adolescents, but only 15% reported a diagnosis, 32% of adolescents reported binge eating, and 20% reported symptoms of clinical depression. No significant associations were found between neurodevelopmental problems and binge eating or depressive symptoms. Only a third of the adolescents reported no problems in either area. Conclusion Two thirds of adolescents seeking surgical weight loss presented with substantial mental health problems (reported by themselves or their parents). This illustrates the importance of a multi‐professional approach and the need to screen for and treat mental health disorders in adolescents with obesity.

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Section: Introductionmentioning

confidence: 84%

Section: Introductionmentioning

confidence: 99%

High prevalence of neurodevelopmental problems in adolescents eligible for bariatric surgery for severe obesity

et al. 2020

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“…Recommendations suggest that significant psychiatric disorders including severe or unstable psychosis and major depressive disorder should be contraindications to bariatric surgery, though few studies have assessed the influence of psychiatric disorders on outcomes after bariatric surgery among adolescents [97,98]. A recent study found that 71% of adolescents who completed a presurgical psychological evaluation for laparoscopic sleeve gastrectomy qualified for a psychiatric disorder with the most common diagnoses being depression (42%) and anxiety (26%) [99]. None of the psychiatric diagnoses predicted percent excess weight loss at 12 months postsurgery.…”

Section: Bariatric Surgerymentioning

confidence: 99%

Obesity in Adolescents with Psychiatric Disorders

Chao

Wadden

Berkowitz

2019

Curr Psychiatry Rep

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Purpose of Review: This narrative review synthesized recent research related to obesity in adolescents with psychiatric disorders, with a focus on epidemiology, mechanisms, and weight management approaches. The paper reviews literature on depressive and anxiety disorders, bipolar disorder, and schizophrenia spectrum and other psychotic disorders. Recent Findings: Depression has a bidirectional relationship with obesity. Bipolar disorder and schizophrenia spectrum disorders, and their treatments, increase the risk of developing obesity. Mechanisms underlying this weight gain include lifestyle and environmental factors and psychiatric medications, though emerging evidence has also suggested the role of genetic and neuroendocrine processes. Evidence about the most effective treatments for obesity in adolescents with psychiatric disorders remains limited. Summary: Adolescents with psychiatric disorders are at high risk for obesity. Close monitoring for increases in weight and cardiometabolic risk factors with use of antipsychotic and moodstabilizing medications is recommended. Clinical trials are needed that test the efficacy of weight management strategies for this population.

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“…Hence, when comparing the prevalence of ADHD between populations, the diagnostic methods should be carefully considered. A study that assessed the prevalence of ADHD among adolescents seeking bariatric surgery was published only recently, used semi‐structured clinical interviews and reported a prevalence of 21% …”

Section: Introductionmentioning

confidence: 99%

“…16 It remains unknown whether the presence of ADHD would affect weight loss and other clinical outcomes in adolescents following bariatric surgery. In the study by Mackey et al, 16 ADHD diagnosis was not related to weight change after bariatric surgery, as previously found in adults. 15,17 However, there is evidence that the presence of behavioural traits associated with ADHD at the time of treatment, such as impulsivity, inattention or hyperactivity, might still be a barrier to successful weight loss during conservative obesity treatment.…”

mentioning

confidence: 99%

High prevalence of attention‐deficit/hyperactivity disorder in adolescents with severe obesity seeking bariatric surgery

et al. 2019

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Aim To examine the prevalence of attention‐deficit/hyperactivity disorder (ADHD) and related post‐surgical weight loss in adolescents with severe obesity seeking bariatric surgery. Methods The study population included 84 adolescents (age 13‐19 years; 44 males, 40 females) with severe obesity who sought bariatric surgery at the Sheba Medical Centre in Israel during the years 2011‐2017. Anthropometric and clinical data were collected from medical records. A subgroup of 20 participants filled questionnaires that evaluated ADHD‐like symptoms, eating behaviours and quality of life. Data on adolescents that ultimately underwent surgery (n = 45) were also obtained. Results The prevalence of ADHD was 28.6% in adolescents seeking bariatric surgery, much higher than that of the general adolescent population of Israel (17.1%, P < .001). There were no significant differences in reductions of weight, body mass index, body mass index standard deviation scores and body fat percent between participants with or without ADHD. In the subgroup that filled questionnaires, higher scores on ADHD‐Rating Scale at baseline were associated with greater excess weight loss. Conclusion The prevalence of ADHD in adolescents seeking bariatric surgery was very high. Diagnosed ADHD was not related to post‐surgical weight loss, whereas baseline ADHD‐related behaviour was associated with higher post‐surgical weight loss.

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Psychiatric Diagnoses and Weight Loss Among Adolescents Receiving Sleeve Gastrectomy

Cited by 23 publications

References 46 publications

High prevalence of neurodevelopmental problems in adolescents eligible for bariatric surgery for severe obesity

High prevalence of neurodevelopmental problems in adolescents eligible for bariatric surgery for severe obesity

Obesity in Adolescents with Psychiatric Disorders

High prevalence of attention‐deficit/hyperactivity disorder in adolescents with severe obesity seeking bariatric surgery

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