in MS has been discussed from epidemiological, clinical, and radiological perspectives (5).Psychiatric symptoms are more frequent in pwMS than in people without it. Mood disorders, such as depression and anxiety are 20% more common. PS is often seen at the time of MS diagnosis and become more severe during the disease (6). Reports estimated that, on average, of pwMS with PS, 30% have depression, 22% anxiety, 13% bipolar mood disorder, 4% psychotic disorder, and 31% obsessive-compulsive disorder. These rates are high compared with the general population (7).Considering the effects of psychiatric symptoms on cognitive performance, physical disability, and fatigue, early diagnosis