Psychiatric illnesses in patients with syncope

Kapoor, Wishwa N.; Fortunato, Michael W-P; Hanusa, Barbara H.; Schulberg, Herbert C.

doi:10.1016/s0002-9343(99)80227-7

Cited by 97 publications

(73 citation statements)

References 27 publications

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“…Predictors of recurrence of syncope include having had recurrent syncope at the time of presentation (four or more episodes in one study [38] ) or a psychiatric diagnosis [38][39][40] . In one study [41] , more than five lifetime episodes gave a 50% chance of recurrence in the following year.…”

Section: Recurrencesmentioning

confidence: 99%

“…Syncope had been unexplained in many of the patients and a large proportion of the patients who received treatment for their psychiatric disorder showed a marked diminution in syncope. More recently, a population-based study [257] showed a 35% prevalence of psychiatric disorders. The most common disorders were generalized anxiety (8·6%), panic disorder (4·3%) and major depression (12·2%).…”

Section: Psychiatric Evaluationmentioning

confidence: 99%

See 1 more Smart Citation

Guidelines on management (diagnosis and treatment) of syncope

Brignole¹,

Alboni²,

Benditt

et al. 2001

European Heart Journal

680

432

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Section: Recurrencesmentioning

confidence: 99%

Section: Psychiatric Evaluationmentioning

confidence: 99%

Guidelines on management (diagnosis and treatment) of syncope

Brignole¹,

Alboni²,

Benditt

et al. 2001

European Heart Journal

680

432

View full text Add to dashboard Cite

“…This may be the consequence of the diffusion of both pathologies. However, the incidence of psychiatric disorders has been reported higher in patients affected by syncope of unknown origin than in general population, and this contrasts with the hypothesis of comorbidity [9].…”

Section: Introductionmentioning

confidence: 81%

“…This symptom is often difficult to evaluate, with a specific cause not established in 10-26 % of the patients despite a wide array of diagnostic tools including head up tilt test (HUTT), ambulatory cardiac monitoring and electrophysiological testing [2,16,17,26]. The possible association between syncope and a psychiatric disorder was suggested over 300 years ago; nevertheless, the relationship between psychiatric disorder and syncope has largely remained unexplored [9,18]. To date, at least three potential explanations for the relationship between syncope and psychiatric disorders can be taken into account.…”

Section: Introductionmentioning

confidence: 99%

Syncope of psychiatric origin

et al. 2004

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“…The association between VVS and psychiatric disorders, though not fully elucidated, has been known for many years [22,23,24]. Panic disorder has been associated with autonomic dysreactivity [25,26,27,28,29,30].…”

Section: Discussionmentioning

confidence: 99%

Minor Psychiatric Disorders and Syncope: The Role of Psychopathology in the Expression of Vasovagal Reflex

Leftheriotis

Michopoulos²,

Flevari³

et al. 2008

Psychother Psychosom

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Background: A high prevalence of minor psychiatric disorders (MPDs) has been reported in patients with vasovagal syncope (VVS). However, the relationship between the psychiatric substrate and syncope remains unclear. Methods: In order to test the hypothesis that MPDs may predispose to VVS, we assessed the prevalence of syncope, the response to head-up tilt test (HUTT) and the efficacy of psychiatric drug treatment in reducing syncopal episodes, in patients with recently diagnosed MPDs. The response to HUTT was compared with that in an equal number of matched (a) patients with VVS and (b) healthy controls. Results: A high rate of patients with MPDs (58%) had a positive HUTT. Additionally, 45% had a history of syncope; among them, the rate of positive HUTT was identical to that in the VVS group (83%). Following psychiatric drug treatment, the number of patients with syncope decreased in the MPD group (6/67 from 30/67, p < 0.01). Psychiatric symptoms and quality of life were also improved. The number of syncopal spells decreased equally in the MPD and VVS groups (0.6 ± 0.5 from 2.5 ± 1.4, p < 0.01, and 0.7 ± 0.5 from 2.7 ± 1.3, p < 0.01, respectively). Conclusion: A high proportion of patients with MPDs experience syncope, associated with a high rate of positive HUTT, comparable to that observed in VVS. Psychiatric treatment results in the improvement of syncopal and psychiatric symptoms. These findings suggest involvement of co-occurring MPDs in the pathogenesis of VVS. Therefore, the diagnosis and treatment of MPDs, when present, may be crucial for the effective therapy of vasovagal syndrome.

show abstract

Psychiatric illnesses in patients with syncope

Cited by 97 publications

References 27 publications

Guidelines on management (diagnosis and treatment) of syncope

Guidelines on management (diagnosis and treatment) of syncope

Syncope of psychiatric origin

Minor Psychiatric Disorders and Syncope: The Role of Psychopathology in the Expression of Vasovagal Reflex

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