Psychogenic pain and depressive disorders: an empirical study

Valdés, Manuel; García, Lluisa; Treserra, J; Pablo, Joan de; Flores, Tomás de

doi:10.1016/0165-0327(89)90050-5

Cited by 18 publications

(4 citation statements)

References 13 publications

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“…Cortisol has also been found to correlate inversely with pain intensity and number of pain sites in chronic pain patients (Morrison et al, 2000). Reduced adrenocortical activity has been documented in patients with chronic pain (Valdes et al, 1989), abdominal pain (Alfven et al, 1994), chronic pelvic pain (Heim et al, 1998), chronic headache (Elwan et al, 1991), low back pain (Theorell et al, 2000), fibromyalgia (Crofford et al, 1994; Griep et al, 1993), rheumatoid arthritis (Chikanza et al, 1992; Hedman et al, 1992), and chronic fatigue syndrome (Demitrack and Crofford, 1998; Demitrack et al, 1991). In light of these interactions between HPA hormones and pain sensitivity and the observed blunted cortisol response to stress in smokers, we propose that the blunted stress response contributed to the enhanced pain sensitivity and absence of stress-induced analgesia in smokers.…”

Section: Discussionmentioning

confidence: 99%

Stress response dysregulation and stress-induced analgesia in nicotine dependent men and women

Al’Absi

Nakajima

Grabowski

2013

Biological Psychology

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Alterations in the stress response and endogenous pain regulation mechanisms may contribute directly and indirectly to maintenance of nicotine dependence and relapse. We examined the extent to which nicotine dependence alters endogenous pain regulatory systems, including the hypothalamic-pituitary-adrenocortical axis, cardiovascular activity, and stress-induced analgesia. Smokers and nonsmokers attended a laboratory session that included assessment of hormonal and cardiovascular responses to stress. Smokers smoked at their regular rate prior to the session. The hand cold pressor and heat thermal pain tests were completed twice, once after acute stress (public speaking and math tasks) and the other after rest. While smokers and nonsmokers exhibited significant hormonal and cardiovascular responses to stress, smokers exhibited blunted stress responses relative to nonsmokers. They also exhibited diminished stress-induced analgesia. Results demonstrate altered stress response and diminished stress-induced analgesia among chronic smokers, and suggest that these dysregulated physiological responding may contribute to altered endogenous pain regulation.

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Section: Discussionmentioning

confidence: 99%

Stress response dysregulation and stress-induced analgesia in nicotine dependent men and women

Al’Absi

Nakajima

Grabowski

2013

Biological Psychology

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“…A limited number of studies have evaluated the effect of antidepressant treatment in somatoform pain. In an open study, Valdés et al (24) treated 31 psychogenic pain patients with imipramine for a period of 5 months. All patients significantly improved in mood and pain after antidepressant treatment.…”

Section: Antidepressants In the Treatment Of Somatoform Painmentioning

confidence: 99%

Somatization and chronic pain

Birket-Smith

2001

Acta Anaesthesiol Scand

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The experience of pain is related not only to tissue damage and physical illness, but also to mental phenomena including depression, anxiety and somatization. Somatization is common among chronic pain patients and presents special problems in management and treatment. Somatoform patients are often given inappropriate diagnoses, treated for non-existent depressive disorders, and exposed to multiple, superfluous investigations. Psychological models of chronic pain and somatization are presented, and treatment issues including psychotherapy and the use of antidepressants are discussed.

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“…Regarding the relationship between depressive symptoms and CP, the prevalence of low back/knee pain was significantly higher in males with than in those without depressive symptoms. Psychogenic pain has been implicated in depression and CP [ 34 , 35 , 36 ]. A study on quantitative sensory tests conducted by depressed patients suggested central hyperexcitability due to decreased serotonin production as a mechanism for CP due to a reduction in the cold pain threshold and an increased responsiveness to repetitive noxious mechanical stimuli [ 37 ].…”

Section: Discussionmentioning

confidence: 99%

Relationship between Alcohol Intake and Chronic Pain with Depressive Symptoms: A Cross-Sectional Analysis of the Shika Study

Amatsu

Tsujiguchi

Hara

et al. 2022

IJERPH

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Although alcohol intake is associated with chronic pain (CP) and analgesia, epidemiological studies have not yet examined the factors affecting the relationship between alcohol intake and CP in detail. Therefore, the present cross-sectional study investigated the relationship between alcohol intake and CP in community-dwelling middle-aged and elderly individuals with/without depressive symptoms. Participants comprised 2223 inhabitants of Shika town in Ishikawa prefecture, located on the Noto Peninsula facing the Sea of Japan, and included 1007 males and 1216 females. CP, depressive symptoms, and alcohol intake were assessed using a CP questionnaire, the Geriatric Depression Scale-15 and the brief-type self-administered diet history questionnaire, respectively. In males without depressive symptoms, mean alcohol intake was significantly higher at 5.70% energy (27.92 g/day) in the CP group than that of 3.75% energy (20.00 g/day) in the non-CP group. The prevalence of low back/knee pain was also significantly higher in males with than in those without depressive symptoms. The present results suggest that long-term alcohol intake is related to CP by reducing the pain threshold and enhancing nociceptive pain as a possible mechanism. However, even a low alcohol intake was associated with psychogenic pain in participants with depressive symptoms. Further studies to investigate the involvement of depressive symptoms and alcohol intake in CP and its prevention are needed.

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Psychogenic pain and depressive disorders: an empirical study

Cited by 18 publications

References 13 publications

Stress response dysregulation and stress-induced analgesia in nicotine dependent men and women

Stress response dysregulation and stress-induced analgesia in nicotine dependent men and women

Somatization and chronic pain

Relationship between Alcohol Intake and Chronic Pain with Depressive Symptoms: A Cross-Sectional Analysis of the Shika Study

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