Psychologic Factors in Psoriasis: Consequences, Mechanisms, and Interventions

Fortune, Dónal G.; Richards, Helen L.; Griffiths, C.E.M.

doi:10.1016/j.det.2005.05.022

Cited by 220 publications

(230 citation statements)

References 107 publications

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“…In addition, these negative feelings are likely to be due to the impaired psychological status, stigmatization and feeling embarrassed because of the appearance of skin lesions in public. Also the result of some studies have shown that psoriasis can cause psychological problems due to stigmatization, depression, anxiety and social problems which support our findings mentioned above (16,(25)(26)(27). In our study, results suggested that RP and RE scales have a significant linear relation with patients' age.…”

Section: Discussionsupporting

confidence: 80%

Assessment of Health-Related Quality of Life in Patients with Psoriasis in Comparison with Normal Subjects in Shiraz Iran

et al. 2014

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Background: Psoriasis is a chronic inflammatory disease, which decreases the health-related quality of life (HRQOL) of the affected patients. There are various determinants related to the patients' HRQOL. Objectives: The objective of this study was to assess the HRQOL of a group of Iranian psoriatic patients in comparison with healthy adults. Patients and Methods: This cross-sectional study was conducted in Shiraz, Iran. Ninety-six psoriatic patients and a control group of 200 healthy subjects were participated in the study. SF-36 questionnaire was used for the data collection. HRQOL was analyzes according to some selected variables including gender, age, education level, duration of the disease, and also in comparison with the control group. Results: Ninety six patients with psoriasis (mean SD age of 35.72 9.95) included 41 males and 55 ty females. The control group had statistically significant (P-Value < 0.001) higher scores in all 8 scales of HRQOL. Physical and emotional role limitation (RP and RP) scales were significantly different in patient group based on the age. Scores forall the 8 scales and 2 summary measures of mental and physical health increased with increasing educational level. Conclusions:The negative impact of psoriasis on various aspects of patients' QOL is an undeniable fact. The results of the present study indicate the necessity of appropriate therapeutic, social and psychological interventions in psoriasis patients in order to help them have better life quality.

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Section: Discussionsupporting

confidence: 80%

Assessment of Health-Related Quality of Life in Patients with Psoriasis in Comparison with Normal Subjects in Shiraz Iran

et al. 2014

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“…Mast cells are increased in lesional psoriatic skin (Özdamar et al, 1996), and have important functions as sensors of environmental and emotional stress (Paus et al, 2006;Harvima et al, 1993) possibly due to direct activation by corticotrophin release hormone (CRH) and related peptides secreted under stress (Theoharides et al, 2004;Katsarou-Katsari et al, 1999;Church & Clough 1999;Harvima et al, 1993;Fortune et al, 2005;Harvima et al, 1996). Psoriasis is associated with increased serum CRH and decreased lesional skin CRHR-1 gene expression (Tagen et al, 2007).…”

Section: Mast Cells and Natural Killer Cells In Plaque Psoriasismentioning

confidence: 99%

Psoriasis, a Systemic Disease Beyond the Skin, as Evidenced by Psoriatic Arthritis and Many Comorbities – Clinical Remission with a Leishmania Amastigotes Vaccine, a Serendipity Finding

O'Daly¹

2012

Psoriasis - A Systemic Disease

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“…Skin pain and discomfort had a negative impact on functions such as sleep, mood and enjoyment of life [16]. Studies suggested that other psoriasis-related sensory skin symptoms were associated with sleep disturbances, psychological distress and impaired health related QoL (HRQoL) [20][21][22][23][24][25].…”

Section: Skin Symptomsmentioning

confidence: 99%

“…The chronic nature of the disease and the lack of control over unexpected outbreaks of the symptoms are among the most bothersome aspects of psoriasis [7]. Patients may feel humiliated when they need to expose their bodies during intimate relationships, swimming, using public showers, or anyway living in conditions that do not provide adequate privacy [8]. Thus psoriasis affects patients' social life, daily activities, and sexual functioning [9].…”

Section: Introductionmentioning

confidence: 99%