Psychological and Somatic Symptoms of Anxiety and Risk of Coronary Heart Disease: The Health and Social Support Prospective Cohort Study

Nabi, Hermann; Hall, Martica; Koskenvuo, Markku; Singh‐Manoux, Archana; Oksanen, Tuula; Suominen, Sakari; Kivimäki, Mika; Vahtera, Jussi

doi:10.1016/j.biopsych.2009.07.040

Cited by 89 publications

(55 citation statements)

References 46 publications

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“…In this study in adults initially free from cardiovascular disease, anxiety, and particularly somatic anxiety, was related to an increased risk of CHD in women but not in men [Nabi et al 2010]. When comparing our results with previous findings on the association of depression dimensions with cardiac disease severity and prognosis in patients with heart disease, our findings are somewhat different.…”

Section: Discussioncontrasting

confidence: 86%

Symptom dimensions of anxiety following myocardial infarction: Associations with depressive symptoms and prognosis.

et al. 2014

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ObjectiveDifferential associations of symptom dimensions with prognosis in myocardial infarction (MI) patients have been shown for depression, but no studies have focused on anxiety dimensions.The aim of this study was to assess the association between somatic and psychological symptoms of anxiety following acute MI with adverse prognosis and to assess the overlap between anxiety and depression dimensions. MethodsPatients (n=418) were assessed on demographic and clinical variables. The Hamilton Anxiety and Depression Rating Scales were used to measure anxiety and depression 2 months post-MI.Mean follow-up period was 3.8 years and the endpoint consisted of all-cause mortality and recurrent MI. ResultsAfter adjustment for demographic and clinical variables, somatic anxiety was significantly associated with recurrent MI and mortality (HR: 1.32; 95% CI: 1.03-1.69; p=0.03), while a trend was shown for an association between psychological anxiety and outcome (HR: 1.29; 95% CI: 0.99-1.67; p=0.06). The total anxiety score of the HARS was the strongest predictor of recurrent MI and mortality (HR: 1.38; 95% CI: 1.07-1.78; p=0.02). The HARS and the HDRS were highly correlated (r=0.86; p<0.01). Dimensions consisting of psychological distress (HR: 1.29; 95% CI:1.02-1.63; p=0.03) and cardiopulmonary/autonomic symptoms (HR: 1.36; 95% CI: 1.06-1.75; p=0.02) also predicted outcome in adjusted analyses. ConclusionsAnxiety was associated with adverse prognosis in MI patients with significant associations for somatic anxiety and total anxiety. When combining anxiety and depression items, psychological distress and cardiopulmonary/autonomic symptoms predicted recurrent MI and mortality. Future 4 research might better focus on dimensions of anxiety and depression simultaneously in MI patients.

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Section: Discussioncontrasting

confidence: 86%

Symptom dimensions of anxiety following myocardial infarction: Associations with depressive symptoms and prognosis.

et al. 2014

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“…A previous review of epidemiologic studies reported that insomnia was associated with an increased risk of coronary heart disease (10). In addition, there is growing evidence that anxiety is an independent risk factor for the development of CAD (11)(12)(13)(14). Therefore, it is possible that nonBDZs can reduce the risk of CAD by relieving insomnia and anxiety.…”

Section: Discussionmentioning

confidence: 99%

Use of Non-benzodiazepine Hypnotics Is Associated with Decreased Risk of Coronary Artery Disease

Zhou

Zhang²,

Chen

et al. 2012

Intern. Med.

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Background It has been reported that the use of benzodiazepines (BDZs) is associated with an increased risk of coronary artery disease (CAD). However, it is still unclear whether or not non-BDZs use has the same adverse effect on the cardiovascular system. Methods We conducted a hospital-based case-control study with 864 CAD patients and 1,008 controls to explore the association between non-BDZs use and CAD risk in Chinese Han population. Results Non-BDZs use was found to be associated with a decreased risk of CAD (adjusted odds ratio, OR= 0.73; 95% confidence interval, CI=0.54-0.98). Adjusted ORs were 0.91 (95% CI=0.63-1.32) for using nonBDZs 0 to 5 years, 0.64 (95% CI=0.38-0.97) for 5 to 10 years, and 0.42 (95% CI=0.18-0.85) for >10 years. The risk of CAD tended to decrease with an increase in duration of non-BDZs use (p<0.001 for trend). Conclusion Our study demonstrates that non-BDZs use is associated with a decreased risk of CAD. The potential cardiovascular protective mechanisms of non-BDZs should be investigated further.

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“…Previous studies showed that psychological factors such as depression, anxiety, and stress play significant role in the etiology, development, duration, and clinical outcomes of CHD (Albus, 2010;KhayyamNekouei et al, 2013). Depression has been found to increase risk for further cardiovascular problems, re-admissions, and mortality among individuals with CHD (Stafford et al, 2009;Jiang et al, 2002), while stress exacerbates their physical and psychological status (Nabi et al, 2010).…”

Section: Introductionmentioning

confidence: 99%

Psychosocial Wellbeing of Patients Diagnosed with Coronary Artery Disease

Ghannam¹,

Hamdan‐Mansour²,

Arabiat³

et al. 2014

PSYCH

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Psychological and social wellbeing of patients diagnosed with coronary heart disease is an important component in patients' recovery. The purpose of this study is to explore the psychological and social factors among individuals diagnosed with coronary artery disease. Methods: 164 patients diagnosed with CHD filled and returned a self administered. Data were collected in regard to stress, depression, perceived social support, and coping. Results: The analysis showed that patients who have moderate level of stress, perceived social support, mild level of depression, have more tendencies to use effective coping strategies. Also the analysis showed that cope, psychological distress, and perceived social support were significant predictors of high level of depression (F = 5.2, p < .001), and that perceived social support from others was the most significant protective factors against depression (F =12.7, p < .001). Conclusion: Mental health care providers need to consider their patients' psychological wellbeing and sources of social support as part of their routine care and assessment. KeywordsPsychosocial Wellbeing, CHD B. M. Ghannam et al. 802

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Psychological and Somatic Symptoms of Anxiety and Risk of Coronary Heart Disease: The Health and Social Support Prospective Cohort Study

Cited by 89 publications

References 46 publications

Symptom dimensions of anxiety following myocardial infarction: Associations with depressive symptoms and prognosis.

Symptom dimensions of anxiety following myocardial infarction: Associations with depressive symptoms and prognosis.

Use of Non-benzodiazepine Hypnotics Is Associated with Decreased Risk of Coronary Artery Disease

Psychosocial Wellbeing of Patients Diagnosed with Coronary Artery Disease

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