Psychological and symptomatic stress-related disorders with Radio Electric Asymmetric Conveyer

Rinaldi, S.; Fontani, V.; Aravagli, L.; Bini, S.; Mannu, P.; Castagna, A.; Margotti, M. L.

doi:10.1037/e572992012-467

Cited by 1 publication

(1 citation statement)

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“…Inflammation has been shown to play an important role in MPTP-induced neurotoxicity [11,12]. Many studies have demonstrated the beneficial effects of the Radio Electric Asymmetric Conveyer (REAC) in neuro-stimulation [13][14][15][16], regenerative medicine [17,18], cognitive disorders [19][20][21][22][23][24][25], and AD [26][27][28], as well as stem cell vitality during aging [29].…”

Section: Introductionmentioning

confidence: 99%

Radio Electric Asymmetric Conveyer Technology Modulates Neuroinflammation in a Mouse Model of Neurodegeneration

et al. 2017

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In this study, the effects of Radio Electric Asymmetric Conveyer (REAC), a non-invasive physical treatment, on neuroinflammatory responses in a mouse model of parkinsonism induced by intoxication with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), were investigated in vivo. We found that the REAC tissue optimization treatment specific for neuro-regenerative purposes (REAC TO-RGN-N) attenuated the inflammatory picture evoked by MPTP-induced nigro-striatal damage in mice, decreasing the levels of pro-inflammatory molecules and increasing anti-inflammatory mediators. Besides, there was a significant reduction of both astrocyte and microglial activation in MPTP-treated mice exposed to REAC TO-RGN-N. These results indicated that REAC TO-RGN-N treatment modulates the pro-inflammatory responses and reduces neuronal damage in MPTP-induced parkinsonism.

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