Chronic kidney disease (CKD) is defined by decreased renal function over time. It can be a progressive condition resulting in endstage renal disease (ESRD). Most research into CKD is based on adult populations. Information on the adolescent population is lacking.Adolescents with CKD are a unique subset of patients with a disease that extends through and beyond traditional paediatric age boundaries into adulthood.Given that this is a crucial time of growth and development, the potential disruption by any disease process can be substantially detrimental to a patient. Since the turn of the century, the incidence rate of ESRD has increased to nearly 25 per million. There are many differences in the clinical manifestation, treatment and progression of CKD among adults compared to adolescents, leading to a potential disruption in care. Thus, further information is required to improve the diagnosis, treatment and prevention of the progression of CKD in adolescents. Given the propensity to lose follow-up during the transition between adolescent and adult care, it can be difficult to conduct long-term follow-up studies on patients. In order to rectify this issue, we look to consolidate available data on adolescent CKD to advance our current knowledge. This review will surmise the different aspects of adolescent CKD, including definition, epidemiology, pathophysiology, cardiovascular manifestations, neurocognitive