Non-local students have been one of the worst affected groups during the COVID-19 pandemic. Many of them live in foreign countries/regions with limited social and economic support. This study examines the effects of the COVID-19 pandemic and its control measures on the well-being of non-local students globally. It also examines the effectiveness of university support for the well-being of non-local students. Data were derived from a global survey on
non-local students’ knowledge, experiences, and well-being amidst the COVID-19 Pandemic,
which was conducted in April 2020 (
n
= 583). A significant proportion (42.6%) of the students had low well-being. We found that being worried about COVID-19 (
B
= − 0.206,
p
= 0.048), perceived disruption of academic activities (
B
= − 0.155,
p
= 0.024), perceived disruption of social activities (
B
= − 0.153,
p
= 0.044), and feeling lonely (
B
= − 0.340,
p
= 0.000) were negatively associated with the students’ well-being. However, informational support from universities was positively associated with their well-being (
B
= 0.225,
p
= 0.004). These findings are discussed in the context of higher education governance and practical changes necessary to promote non-local students’ well-being during and after the pandemic.