Psychological distress as a crucial determinant for quality of life in patients with noncardiac chest pain in Central China

Zhang, Lei; Tu, Lei; Chen, Jie; Bai, Tao; Song, Jun; Xiang, Xuelian; Wang, Ruiyun; Hou, Xiaohua

doi:10.1097/md.0000000000005289

Cited by 4 publications

(2 citation statements)

References 29 publications

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“…We found that HRQoL was associated with cardiac anxiety, depressive symptoms and somatization, supporting previous results [44]. Both cardiac anxiety and depressive symptoms have been found to predict continued chest pain in NCCP patients [7,15], thus leading to reduced HRQoL.…”

Section: Discussionsupporting

confidence: 90%

The associations between psychological distress and health-related quality of life in patients with non-cardiac chest pain

Mourad

Alwin

Jaarsma

et al. 2020

Health Qual Life Outcomes

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Background: Recurrent chest pain episodes with no clear explanation may affect patients' psychological wellbeing and health-related quality of life (HRQoL) negatively. Despite the fact that a significant amount of patients with non-cardiac chest pain (NCCP) might have a history of Cardiac Disease (CD), there is today a lack of knowledge on how CD influences the association between psychological wellbeing and HRQoL in patients with NCCP. Therefore, the aim of this study is to describe HRQoL in patients with NCCP, with or without history of CD, and to explore the association between HRQoL and cardiac anxiety, depressive symptoms, fear of body sensations and somatization. Methods: Five hundred fifty-two patients discharged with NCCP from four hospitals in Southeast Sweden completed the EQ-5D, Cardiac Anxiety Questionnaire, Patient Health Questionnaire-9, Body Sensations Questionnaire, and Patient Health Questionnaire-15. Results: Fifty precent reported at least moderate problems regarding pain/discomfort and 25% reported at least moderate problems in the HRQoL dimensions mobility, usual activities, and anxiety/depression. Patients with NCCP and history of CD reported significantly lower HRQoL (p ≤ 0.05) compared to patients with NCCP without CD. In the total study population, cardiac anxiety, depressive symptoms, and somatization had weak significant negative associations (beta = 0.187-0.284, p < 0.001) with HRQoL. In patients with history of CD, the association between depressive symptoms and HRQoL was moderate (beta = − 0.339, p < 0.001), compared to weak association in patients without CD (beta = − 0.193, p < 0.001). On the other hand, the association between cardiac anxiety and HRQoL was weak in both patients with history of CD (beta = − 0.156, p = 0.05), and in those without (beta = − 0.229, p < 0.001). Conclusions: Patients with NCCP, in particular those with history of CD, reported low levels of HRQoL, which was associated with psychological distress. This should be considered when developing psychological interventions aiming to improve HRQoL in patients with NCCP.

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Section: Discussionsupporting

confidence: 90%

The associations between psychological distress and health-related quality of life in patients with non-cardiac chest pain

Mourad

Alwin

Jaarsma

et al. 2020

Health Qual Life Outcomes

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“…The Chinese version of the SF-36 questionnaire is available and provided by the developer. The tool’s validity and screening ability have been documented in various samples in the People’s Republic of China 15,16…”

Section: Methodsmentioning

confidence: 99%

Health-related quality of life in patients with chronic hepatitis B during antiviral treatment and off-treatment

Xue¹,

Cai²,

Ou³

et al. 2017

PPA

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IntroductionHealth-related quality of life (HRQoL) has emerged as an important consideration in the care of patients with chronic hepatitis B (CHB). However, whether benefits from the improved HRQoL that occurs after antiviral treatment or drug discontinuation outweigh the risks of viral relapse is an unanswered question. The aim of this study was to evaluate the HRQoL among patients with CHB during antiviral treatment and withdrawal of treatment.Patients and methodsThere were 102 patients who met the enrollment criteria with 54 patients in the treatment group and 48 patients in the discontinuation group. Sociodemographic information was collected. The 36-Item Short-Form Health Survey (SF-36), European Quality of Life-5 Dimensions, and Beck Depression Inventory (BDI) were adopted to evaluate life quality and mental health.ResultsIn the treatment group, SF-36 showed that the physical functions were significantly increased. In the discontination group, the psychological functions showed improvement. A multivariate regression analysis indicated that baseline SF-36 score was a predictor for improvement in HRQoL (odds ratio =1.17, P=0.003) and baseline BDI score was a factor for remission of depression (odds ratio =0.75, P=0.005) after medical intervention. When the cutoff value of SF-36 score was set at 79.5, the sensitivity and specificity to predict improvement in HRQoL were 82.8% and 74.0%, respectively. When the cutoff value of BDI was found as 8.5, the sensitivity and specificity to predict alleviation of depression were 58.6%, and 76.0%, respectively.ConclusionAntiviral treatment benefits the physical health of the patients with CHB, while conferring no obvious improvement in their psychological condition. Improved psychological interventions for patients with CHB, especially for those with lower baseline SF-36 scores and higher BDI scores, may improve their quality of life.

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Noncardiac chest pain

Yamasaki

Fass

2017

Current Opinion in Gastroenterology

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GERD is the most common esophageal cause of NCCP, followed by functional chest pain and esophageal dysmotility. The proton pump inhibitor test, upper endoscopy, wireless pH capsule and pH-impedance are used to identify GERD-induced NCCP. High-resolution esophageal manometry is the main tool to identify esophageal motor disorder in non-GERD-related NCCP. Negative diagnostic assessment suggests functional chest pain. Potent antireflux treatment is offered to patients with GERD-related NCCP; medical, endoscopic or surgical interventions are considered in esophageal dysmotility; and neuromodulators are prescribed for functional chest pain. Assessment and treatment of psychological comorbidity should be considered in all NCCP patients.

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Psychological distress as a crucial determinant for quality of life in patients with noncardiac chest pain in Central China

Cited by 4 publications

References 29 publications

The associations between psychological distress and health-related quality of life in patients with non-cardiac chest pain

The associations between psychological distress and health-related quality of life in patients with non-cardiac chest pain

Health-related quality of life in patients with chronic hepatitis B during antiviral treatment and off-treatment

Noncardiac chest pain

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