Psychological factors are more strongly associated with pain than radiographic severity in non-invasively treated first carpometacarpal osteoarthritis

Hoogendam, Lisa; Tsehaie, Jonathan; Wouters, Robbert M.; Vermeulen, Guus M.; Slijper, Harm P.; Selles, Ruud W.; Porsius, Jarry T.

doi:10.1080/09638288.2019.1685602

Cited by 33 publications

(32 citation statements)

References 41 publications

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“…One study found that this difference could be explained by the difference in pain-related anxiety 33 . This hypothesis is supported by an analysis by Hoogendam et al 34 in CMC1 OA, who reported that psychosocial factors are associated with pain, but not the radiographic severity. Studying which factors determine if patients seek care for symptomatic thumb base OA could provide clinicians with an opportunity to simultaneously treat this underlying disease processes alongside the changes in bone morphology.…”

Section: Osteoarthritis Andcartilagementioning

confidence: 60%

The prevalence of radiographic thumb base osteoarthritis: a meta-analysis

Oest

Duraku

Andrinopoulou

et al. 2021

Osteoarthritis and Cartilage

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Introduction: Osteoarthritis (OA) affects millions of people worldwide. In hand OA, the thumb base is the most affected single joint. The reported radiographic prevalence ranges from 0 to 100%, making the true radiographic prevalence unclear. Hence, we conducted a meta-analysis on the age and sex-specific prevalence of radiographic thumb base OA. Methods: We performed a search in Embase, Medline Ovid, Web of Science Core Collection, Cochrane Central Register of Trials, and Google Scholar. We included studies of the general population that reported thumb base OA for males and females separately based on a hand radiograph and reported the age of these groups. Using meta-regression, we estimated the odds ratio (OR) of having radiographic thumb base OA for age and sex, while adjusting for within-study correlation. Results: The initial search yielded 4,278 articles; we finally included 16 studies that reported the age-and sex-stratified prevalence. Taken together, there were 104 age and gender specific-prevalence rates that could be derived from the 16 studies. The prevalence of radiographic OA for the 50-year-old male and female participants was 5.8% and 7.3%, respectively, while the respective prevalence for 80-year-old male and female participants was 33.1% and 39.0%. We found an OR for having radiographic OA of 1.06 (95%CI [1.055e1.065], p < 0.001) per increasing year of age, and 1.30 (95%CI: 1.05e1.61], p ¼ 0.014) for females. Conclusion: In the general population, radiographic thumb base OA is more prevalent in females and is strongly associated with age.

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Section: Osteoarthritis Andcartilagementioning

confidence: 60%

The prevalence of radiographic thumb base osteoarthritis: a meta-analysis

Oest

Duraku

Andrinopoulou

et al. 2021

Osteoarthritis and Cartilage

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“…However, in these studies post-treatment PROMs were not adjusted for pre-treatment PROMs, which might explain the difference with our own findings. As CMC-1 OA complaints are known to be associated with pain catastrophizing and psychological distress before treatment [38], it may be worthwhile to further investigate potential indirect pathways through which these mindset variables affect treatment outcomes in CMC-1 OA.…”

Section: Discussionmentioning

confidence: 99%

Associations between positive treatment outcome expectations, illness understanding, and outcomes: a cohort study on non-operative treatment of first carpometacarpal osteoarthritis

Oest

Hoogendam

Wouters

et al. 2021

Disability and Rehabilitation

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Purpose: More positive outcome expectations and illness perceptions are associated with better outcomes for patients with several osteoarthritic orthopedic conditions. However, it is unknown whether these factors also influence outcomes of non-operative treatment for first carpometacarpal osteoarthritis (CMC-1 OA). Therefore, we assess the role of pre-treatment outcome expectations and illness perceptions in reports of pain and hand function 3 months after non-operative treatment for CMC-1 OA. Materials and methods: We conducted a cohort study with 219 patients treated non-operatively for CMC-1 OA between September 2017 and October 2018. Patients were included in the study if they completed measures of pain and hand function, illness perceptions (scale: 0-10), and expectations (scale: 3-27) as part of routine outcome measurements. Pain and hand function were measured before treatment and 3 months after starting treatment using the Dutch version of the Michigan Hand Outcomes Questionnaire. Multivariable linear regression analysis was used to assess the influence of outcome expectations and illness perceptions on pain and hand function. Results: Both positive outcome expectations (B ¼ 0.64; 95% CI [0.1-1.2]) and a better illness understanding (an illness perception subdomain; B ¼ 1.53; 95% CI [0.2-2.9]) at baseline were associated with less pain at 3 months. For hand function, similar estimates were found. Conclusions: We found that positive outcome expectations and a better illness understanding, were associated with a better outcome of non-operative treatment for CMC-1 OA. ä IMPLICATIONS FOR REHABILITATIONNon-operative treatment can often be successful for patients with arthritis of the thumb. Outcome expectations and illness perceptions are associated with pain and hand function 3 months after non-operative treatment for thumb base osteoarthritis. Improving the outcome expectations and illness perceptions of patients through better education could improve the outcome of non-operative treatment.

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“…People with hand OA frequently seek medical care due to ongoing pain and disability [ 3 ]. It is therefore important to improve our ability to identify and classify different types of pain in order to develop more effective treatment plans [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

Neuropathic Pain in Hand Osteoarthritis: A Cross-Sectional Study

Magni

Collier

McNair

et al. 2021

JCM

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Symptomatic hand osteoarthritis (OA) is a severely debilitating condition. Neuropathic pain (NP) has been shown to be a factor affecting pain severity, hand function, psychological wellbeing, body schema, and the number of pain medications in people with OA of other joints. The aim of this study was to assess the prevalence of NP in symptomatic hand OA and assess its association with pain, hand function, measures of psychological wellbeing, sleep, body schema disturbances, and number of pain medications. Participants with symptomatic hand OA diagnosed through the American College of Rheumatology criteria, were recruited and completed a series of online questionnaires. These included the Douleur Neuropathique 4 interview (DN4-interview), Short Form Brief Pain Inventory (SF-BPI), Neglect-like Symptoms questionnaire, Functional Index of Hand Osteoarthritis (FIHOA), Centre for Epidemiologic Studies Depression Scale (CES-D), Pain Catastrophising Scale (PCS), and the Pittsburgh Sleep Quality Index (PSQI). Logistic regression with age, body mass index, and sex as covariates were utilised to assess differences between participants with and without NP as identified through the DN4-interview. Correlation analysis assessed the relationship between pain intensity, body schema alterations, and number of pain medications. A total of 121 participants were included in the present study. Forty-two percent of participants presented with NP. Participants with NP reported higher levels of worst pain (OR: 10.2 95%CI: 2.2 to 48.5; p = 0.007). Worst pain intensity correlated with the number of pain medications (rho = 0.2; p = 0.04), and neglect-like symptoms (rho = 0.4; p < 0.0001). No difference between phenotypes was shown for catastrophising, function, depression, neglect-like symptoms, pain interference, or sleep. A large proportion of people with symptomatic hand OA present with NP. This phenotype is characterised by greater levels of pain intensity. Pain intensity is associated with number of pain relief medications and body schema alteration. Psychological factors, hand function, and sleep do not appear to be affected by the presence of NP.

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Psychological factors are more strongly associated with pain than radiographic severity in non-invasively treated first carpometacarpal osteoarthritis

Cited by 33 publications

References 41 publications

The prevalence of radiographic thumb base osteoarthritis: a meta-analysis

The prevalence of radiographic thumb base osteoarthritis: a meta-analysis

Associations between positive treatment outcome expectations, illness understanding, and outcomes: a cohort study on non-operative treatment of first carpometacarpal osteoarthritis

Neuropathic Pain in Hand Osteoarthritis: A Cross-Sectional Study

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