“…Patients' pre-surgical psychological profiles may play a major role in determining the long-term efficacy of surgery by affecting the recovery process 13,32,40,45,59,60,68,[78][79][80] . Specifically, preoperative levels of fear of pain 41,79 , pain catastrophizing 22,80,87 , depression 11,20,63,64,68 , optimism 55 , self-efficacy 18,86,88 , kinesiophobia 20 , and anxiety 6,20 have been suggested to explain some of the variability in outcomes, such as pain intensity and function, following arthroplasty and may represent promising avenues for future interventions. Nevertheless, there is considerable heterogeneity in these findings, which has cast doubt onto the presence of true effects 40,87 .…”