“…For psychosocial risk factors, these interactions may be due to the presence of personality features associated with the development of AN and high educational/income attainment, such as perfectionism (Cassin & von Ranson, 2005;Madigan, 2019), autonomy (i.e. independence, control, and need for achievement; Cassin & von Ranson, 2005; de la Fuente, Malpica-Chavarria, Garzon-Umerenkova, & Pachon-Basallo, 2021; Shi & Qu, 2021), neuroticism/anxiety (Kienngam et al 2022;Marzola, Porliod, Panero, De-Bacco, & Abbate-Daga, 2020;Tucker-Drob, Briley, Engelhardt, Mann, & Harden, 2016), and harm avoidance (Cassin & von Ranson, 2005). The limited number of interactions observed in the present study should be interpreted in light of the challenges of using PRS to examine interactions: namely, limited statistical power and the potential that phenotypic PRS may not necessarily capture genetic variations associated with differential exposure to risk factors (Zhang & Belsky, 2022).…”